“…W orldwide, it is estimated that 2.1 to 5 million children under 15 years of age have chronic hepatitis C virus (HCV) infection. (1,2) In children, chronic HCV infection is often asymptomatic or with mild, nonspecific symptoms. However, progression to significant fibrosis can occur, (3) and cases of cirrhosis, (4)(5)(6) hepatocellular carcinoma, (7,8) and end-stage liver disease requiring liver Abbreviations: AUC, area under the curve; BMI, body mass index; CI, confidence interval; GT, genotype; HCV, hepatitis C virus; INR, international normalized ratio of prothrombin time; NI, nucleotide inhibitor; NS5B, nonstructural protein 5B; PK, pharmacokinetic; R AS, resistance-associated substitution; RBV, ribavirin; SOF, sofosbuvir; SVR, sustained virological response.…”