Hepatitis C virus transmitted by human bite

Risk and Management of Blood-Borne Infections in Health Care Workers

“…Saliva may contain HCV but has not been epidemiologically linked to transmission. HCV RNA has not been detected in urine, feces, or vaginal secretions from patients who have virus circulating in the blood (96,144). The relatively few studies examining risk factors for infection and conflicting results highlight the need for further studies to better define the factors influencing infectivity and risk factors for acquiring HCV infection among HCWs.…”

Sialadenitis histologically resembling Sjögren syndrome in mice transgenic for hepatitis C virus envelope genes

“…HCV infection may account for the pathogenesis of a subgroup of Sjögren syndrome, which is considered to be a multifactorial disease (33,34). Although the HCV genes were expressed under the control of an exogenous promoter in these transgenic mice, the presence of HCV in human saliva has been reported either through the detection of HCV in human saliva or transmission of hepatitis via saliva (37)(38)(39) sialadenitis and suggest a direct role of the viral protein(s) in the pathogenesis of sialadenitis that develops in chronic HCV infection. This mouse system might be a good animal model for studying the pathogenesis of sialadenitis and other HCVassociated extrahepatic manifestations.…”

Four Cases with Intrafamilial Clustering of Hepatitis C Virus Infection.

“…In Case 3, an ordinary household contact was likely the route of HCV infection. Recently, the transmission of HCV through saliva via a human bite was reported (12 be important in the intra familial spread of HCV. Six family members including the index patients were positive for three types of HCV markers, three members for two of the three types, and two members only for anti-C100-3 or anti-CP9.…”