Hepatitis E Virus Antibody Prevalence in Wildlife in Poland

Larska, Magdalena; Krzysiak, Michał; Jabłoński, Artur; Kęsik, J.; Bednarski, Michał; Rola, J.

doi:10.1111/zph.12113

Cited by 41 publications

(51 citation statements)

References 25 publications

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“…Larska et al (9) demonstrated that the percentage of seropositive wild boars was 44.4% and HEV antibodies were found in the animals from 52 out of 94 hunting sites. Significant variation in the percentages of seropositive wild boars from different provinces was observed.…”

Section: Discussionmentioning

confidence: 99%

“…The highest percentages of seropositive wild boars of 88.2% and 84.2% were found in the West Pomerania and Lower Silesia Provinces, respectively. In the study by Larska et al (9), HEV antibody prevalence in wildlife in Poland was determined in 11 out of 16 provinces of Poland. The samples were collected in 2012-2013 during the classical swine fever monitoring programme.…”

Section: Discussionmentioning

confidence: 99%

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Preliminary study on the detection of hepatitis E virus (HEV) antibodies in pigs and wild boars in Poland

Weiner

Tokarska-Rodak

Plewik³

et al. 2016

Journal of Veterinary Research

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Introduction: Although HEV infection in pigs does not pose a major economic risk to pork production, the risk of zoonotic transmission to humans is an important aspect of public health. HEV genotype 3 infections were reported in developed countries in individuals who had consumed raw meat or meat products from deer, wild boars, or pigs. The aim of the study was the analysis of the occurrence of HEV-specific antibodies among wild boars and domestic pigs in Poland. Material and Methods: A total of 290 samples from wild boars and 143 samples from pigs were tested. The antibodies were tested by ELISA. Results: The presence of anti-HEV IgG was demonstrated in 44.1% of pigs and 31.0% of wild boars. Anti-HEV IgG antibodies were detected in 1.4% of samples from pigs and in 2.1% of samples from wild boars at borderline level. The statistical analysis shows significant differences in the positive results for anti-HEV IgG between the groups of pigs and wild boars (P = 0.0263). Conclusion: Regular surveillance of the occurrence of HEV in swine and wild boars should be performed in the future.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Preliminary study on the detection of hepatitis E virus (HEV) antibodies in pigs and wild boars in Poland

Weiner

Tokarska-Rodak

Plewik³

et al. 2016

Journal of Veterinary Research

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“…In Spain, an apparent seroprevalence of 10.4% was observed in 968 red deer (Boadella et al 2010), in Italy -5.6% of 54 red deer (Mazzei et al 2015b), and in Belgium -1% of 189 red deer (Thiry et al 2015). The HEV specific antibodies were detected in serum of 5% of 38 red deer and none of 8 roe deer studied in Netherlands (Rutjes et al 2010); whereas in Poland, no antibodies were detected in 118 red deer and 38 roe deer serum samples (Larska et al 2015). We have estimated a 1.2% HEV seroprevalence in Lithuanian roe deer and this result was partially in line with Thiry et al (2015) who determined 3% of 235 roe deer to be seropositive in Belgium.…”

Section: Discussionmentioning

confidence: 97%

“…A Polish study determined 44.4% of HEV antibodies in the serum of wild boar from 11 different Polish provinces (Larska et al 2015), while a Spanish study found an overall seroprevalence of 42.7% in wild boar population from South Central Spain, whereas IgG seroprevalence ranged from 0% to 63.3% depending on geographical region. On the other hand, overall seroprevalence in wild boar population in Switzerland and Croatia was reported to be 12.5% (Burri et al 2014) and 12.3% (Prpic et al 2015) of all tested samples, respectively.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of hepatitis E virus in Lithuanian domestic pigs and wildlife

Spancernienė

Buitkuvienė²,

Grigas

et al. 2016

Acta Vet. Brno

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Hepatitis E is an important public health concern disease that causes acute hepatitis in humans with different hepatitis E virus strains reported among domestic and wild animals. In Lithuania, seroprevalence studies on animals considered to be possible virus reservoirs, particularly in wildlife species, had never been investigated before. In order to assess the actual distribution of the virus in the domestic pig and wildlife species, serum samples originating from different geographic areas of Lithuania were tested for the presence of antibodies to the virus using enzyme-linked immunosorbent assay. The study results proved that hepatitis E virus infection is prevalent among domestic pigs, wild boar, moose, and roe deer in Lithuania, with the overall prevalence of IgG antibodies against hepatitis E virus being 43.75%, 57.05%, 11.76%, and 1.20%, respectively. Significantly higher (P < 0.01) seroprevalence values of 53.66% and 80% were observed in weaned pigs and adult wild boar. Herds with 15 001-30 000 pigs were 2.4 times more likely (P < 0.01) to test positive for hepatitis E virus antibodies (70.18%), than herds with ≤ 500 pigs (21.11%). The differences in seroprevalence rates between domestic pigs (from 25 to 66.67%) and wild boar (from 42.86 to 73.33% ) in all 10 counties were not significant (P > 0.05). Estimated low seroprevalence rate in moose, roe deer and absence of antibodies in red deer suggest that such wildlife species are accidental hosts of hepatitis E virus or at least hepatitis E virus is not present in Lithuanian cervides. HEV, sow, wild boar, cervidae, serum, zoonosisAccording to data reported by the World Health Organization (2015), in humans there are estimated 20 million cases of hepatitis E infections, over 3 million symptomatic cases of hepatitis E, and 56 600 hepatitis E-related deaths every year. Therefore, hepatitis E is considered an emerging zoonotic disease in many developing and industrialized countries. The aetiological agent of the disease is hepatitis E virus (HEV) that affects multiple hosts. The HEV is unique among known hepatitis (A, B, C, D) viruses because domestic pigs, wild boar, deer, and other animal species are considered to be possible reservoirs of HEV. Up to date, at least seven genotypes of HEV have been reported, and five of them have been described in humans (HEV-1 and HEV-2 anthroponotic, HEV-3 and HEV-4 zoonotic, HEV-7 zoonotic potential is still being questioned) (Roth et al. 2016). In contrast to humans, pigs and wild boar infected by HEV do not show obvious clinical manifestations.The consumption of raw or undercooked contaminated meat of domestic pig, wild boar or deer and also seafood receiving sewage sludge or direct contact with infected animals have been identified as modes of transmission linked to autochthonous sporadic cases of acute hepatitis E in humans (Pavio et al. 2010;Kaba et al. 2013). Moreover, increased distribution and availability of game meat poses a major risk for foodborne transmission of HEV worldwide. In addition,

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“…W Europie seroprewalencja wynosi od 12% w populacji tych zwierząt w Holandii do 42,7% w Hiszpanii (13,57). W Polsce badania przeprowadzane na populacji dzików pochodzących z obszaru środkowej i zachodniej części kraju wskazały na obecność przeciwciał u 44,4% badanych zwierząt (30). Przeciwciała anty-HEV wykazano również u jeleni i saren, jednak seroprewalencja w europejskiej populacji dzikich przeżuwaczy nie przekraczała 6,8% (46,70).…”

Section: Hev U Ptakówunclassified