Hepatitis Following Blood or Plasma Transfusions

Homologous Serum Jaundice

“…Few, if any, of the cases were bad enough to go to hospital or to be attended closely by their own doctor; the account of their symptoms is therefore neither detailed nor extremely reliable. It does not differ in any striking way from that described by previous observers (Steiner, 1944;Rappaport, 1945).…”

Homologous Serum Jaundice

“…Few, if any, of the cases were bad enough to go to hospital or to be attended closely by their own doctor; the account of their symptoms is therefore neither detailed nor extremely reliable. It does not differ in any striking way from that described by previous observers (Steiner, 1944;Rappaport, 1945 It is suggested tlt to minimize the risk of homologous serum jaundice after transfusion the following procedure should be adopted: (i) human serum for prophylactic purposes should not be pooled; (ii) for transfusion purposes only small pools should. be used*; (iii) all blood products issued should carry an identification number; (iv) records should be kept of the number of any bottle given to a particular patient; (v) machinery should be maintained and strengthened for the notification to the regional transfusion officer of jaundice following transfusion, thus enabling icterogenic material to be withdrawn from circulation.…”

“…Steiner (1244) records three cases following whole blood alone and two following plasma also. Rappaport (1945), in a series of 33 cases of jaundice after transfusion, mentions two who were given blood only. Loutit and Maunsell (1945) found no case of frank homologous serum jaundice in a follow-up of a selected series of 213 blood transfusions.…”

In vitro investigation of the origin of echoes within biliary sludge

“…The clinical implications of these observations are more difficult to assess. For many years clinicians have examined bile collected from patients by a tube passed perorally into the duodenum (the Meltzer-Lyon test) (13,(19)(20)(21)(22)(23)(24)(25)(26)(27). When gallbladder bile contains cholesterol crystals or calcium bilirubinate granules in moderate to large amounts, there is a strong correlation with the presence of gallstones in the gallbladder or some other abnormality, such as cholesterolosis (19)(20)(21).…”