Hepatobiliary and Pancreatic: Intrapancreatic splenunculus mimics a hypervascular neoplasm

Chanyaputhipong, Jendana; Sittampalam, Kesavan; Goh, Brian K. P.; Cheow, Peng‐Chung

doi:10.1111/jgh.12014

Cited by 2 publications

(1 citation statement)

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“…[ 2 ] Now there exist nearly ten different types of Gd-chelates serving as clinical T 1 contrast agents. [23][24][25] Similar to organic chelating agent, some inorganic compounds can fi rmly hold Gd 3+ ions to prevent them from being dissolved in aqueous media even in NP forms. [ 18 ] In comparison with Gd-complexes, Gd 3+ -containing inorganic NPs exhibit much higher longitudinal relaxivities r 1 per particle due to the presence of a large number of paramagnetic Gd 3+ ions per particle.…”

Section: Gadolinium-based Npsmentioning

confidence: 99%

Small is Smarter: Nano MRI Contrast Agents – Advantages and Recent Achievements

Gao

Zhao

et al. 2015

Small

162

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Many challenges for advanced sensitive and noninvasive clinical diagnostic imaging remain unmatched. In particular, the great potential of magnetic nano-probes is intensively discussed to further improve the performance of magnetic resonance imaging (MRI), especially for cancer diagnosis. Based on recent achievements, here the concepts of magnetic nanoparticle-based MRI contrast agents and tumor-specific imaging probes are critically summarized. Advances in their synthesis, biocompatible chemical and biofunctional surface modifications, and current strategies for further developing them into multimodality imaging probes are discussed. In addition, how engineered versus unintended surface coatings such as protein coronas affect the biocompatibility and performance of MRI nano-probes is also considered. To stimulate progress in the field, future strategies and relevant challenges that still need to be resolved in the field conclude this review.

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Section: Gadolinium-based Npsmentioning

confidence: 99%