Hepatobiliary cystadenoma: A rare hepatic tumor in a child

Mucinous biliary cystadenoma with mesenchymal stroma: Expressions of CA 19-9 and carcinoembryonic antigen in serum and cystic fluid

“…Wheeler and Edmondson hypothesize that these tumors arise from ectopic remnants of embryonic bile ducts. [6][7][8][9][10][11] Biochemical tests in this case revealed, high serum CA 19-9 (108U/ml) with normal alpha-fetoprotein and CEA, which is consistent with a previous study. 7 A 7430U/ml level of CA 19-9 in cystic fluid corresponds well with a high level of 108 U/ml in the serum.…”

Hepatobiliary mucinous cystadenoma in a child

“…7 Recently, the recurrence of the incompletely excised lesions and finding of adenocarcinoma foci in cysts that otherwise contain benign-appearing epithelial elements, have mandated complete excision of cystadenomas for treatment. 1,7 Our steps that we have taken prove that the surgical policy should be complete excision of the tumor instead of some types of palliative measurements because of complications that we have encountered in this case. The excessive mucin production of the tumor was the main cause of huge mucinous ascites collected in the abdominal cavity.…”

“…1,3 Although some types of hepatobiliary tumors, including cholangiocarcinoma, hepatobiliary cystadenoma, and cystadenocarcinoma, produce mucin in varying amounts, the term mucin-hypersecreting has been applied traditionally to a pancreatic carcinoma. [7][8][9][10][11] In these cases, the mucin rather than the tumor itself determines the clinical course by either creating obstructing jaundice giving to the bile stasis of the communicated bile ducts or the mass effect of the excess mucinous fluid in the tumor.…”

“…[1][2][3][4][5][6] We present the case of a large mucin-hypersecreting hepatobiliary neoplasm in a child, which was presented as a complex unresectable tumor.…”

Fine needle aspiration cytology of hepatobiliary cystadenoma with mesenchymal stroma

“…4 The subepithelial MS cells in all patients in the current study showed moderate to strong reactivities to ER stains, while all but one patient showed mild to strong reactions to PR stains (Table 2), as consistent with previous reports. 9,10 Although non-specific cytologic findings were briefly mentioned in two reports of HBC, 11,12 to the best of our knowledge, the cytomorphology of HBC with or without MS has not yet been thoroughly described. Upon aspiration, cytologic analysis of the fluid consistently exhibited chronic inflammatory exudate with large numbers of neutrophils, lymphocytes, and macrophages along with a few groups of non-atypical, often degenerated, cuboidal to columnar epithelial cells in a hypocellular pattern, which occasionally were arranged in papillary clusters.…”