Hepatobiliary scintigraphy for the assessment of biliary stricture after pediatric living donor liver transplantation for hepaticojejunostomy reconstruction: The value of the excretion rate at 60 min

Fukuda, Akira; Sakamoto, Seisuke; Shigeta, Takanobu; Kakiuchi, Toshihiko; Matsuno, Naoto; Tanaka, Hideaki; Kitamura, Masayuki; Nosaka, Shunsuke; Nakazawa, Atsuko; Kasahara, Mureo

doi:10.1111/j.1399-3046.2011.01532.x

Cited by 5 publications

(4 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Cumulative incidence of cholangitis (a) and hepatolithiasis (b) in the cholestasis and non-cholestasis groups adults, hepatobiliary scintigraphy is used to evaluate bile excretion after surgery for biliary tract cancer [9,10,25]. Furthermore, the reliability of biliary stenosis diagnosis following liver transplantation in children is reportedly improved by the use of combined ultrasonography and biliary scintigraphy [8]. One description of a CC case reported that biliary scintigraphy could be used to diagnose cholestasis and elucidate the cause of symptoms in patients who developed postoperative cholangitis.…”

Section: Discussionmentioning

confidence: 99%

“…99m Tc-N-pyridoxyl-5-methyltryptophan ( 99m Tc-PMT) hepatobiliary scintigraphy is a minimally invasive diagnostic imaging method that physiologically evaluates bile flow dynamics. It has been used for the postoperative evaluation of cholangiocarcinoma surgery in adults and liver transplantation in children [8][9][10]. However, the usefulness of 99m Tc-PMT hepatobiliary scintigraphy after pediatric CC surgery has not been systematically evaluated.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

et al. 2022

View full text Add to dashboard Cite

Purpose Hepatobiliary scintigraphy is a minimally invasive imaging method that evaluates bile flow dynamics. At our hospital, it has been performed for postoperative evaluation of patients with choledochal cysts (CC). This study evaluated the usefulness of biliary scintigraphy for predicting late complications in patients with CCs. Methods The study included pediatric patients with CC who underwent surgery at Chiba University Hospital from 1978 to 2020, followed by postoperative biliary scintigraphy and subsequent radiologic evaluation. The patients were divided into two groups according to the presence or absence of “biliary cholestasis” on biliary scintigraphy. Results The study included 108 patients, with a median age at surgery of 2 years and 11 months. The median follow-up period was 5203 days, with 11 hepatolithiasis cases and 8 cholangitis cases. No patients had cholangiocarcinoma. Twelve patients were considered to have “cholestasis” following biliary scintigraphy evaluation. There was no significant difference in the occurrence of hepatolithiasis between the cholestasis and non-cholestasis groups (p = 0.47), but cholangitis was significantly more common in the cholestasis group (p = 0.016). Conclusion Biliary cholestasis on postoperative hepatobiliary scintigraphy was a risk factor for cholangitis in patients with CCs. These particular patients should be monitored carefully.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

et al. 2022

View full text Add to dashboard Cite

show abstract

“…28 The deposit of the tracer at 60 minutes after intravenous injection is considered normal more than 80% of the tracer excretes from intrahepatic biliary duct to the lower afferent loop jejunum. 29–30 If excretion of the tracer to the intrahepatic biliary ducts has not taken place within 60 minutes, a diagnosis of liver dysfunction is given, 30–32 and if stasis of the tracer occurs in the intrahepatic biliary duct, it is thought to be caused by hepaticojejunostomy anastomotic stenosis. 29–30 On the other hand, if stasis of the tracer occurs in the upper afferent loop jejunum, it is thought to be caused by afferent loop syndrome.…”

Section: Discussionmentioning

confidence: 99%

Recurrent Cholangitis by Biliary Stasis Due to Non-Obstructive Afferent Loop Syndrome After Pylorus-Preserving Pancreatoduodenectomy: Report of a Case

Sanada

Yamada

Taguchi

et al. 2014

International Surgery

View full text Add to dashboard Cite

We report a 71-year-old man who had undergone pylorus-preserving pancreatoduodenectomy (PPPD) using PPPD-IV reconstruction for cholangiocarcinoma. For 6 years thereafter, he had suffered recurrent cholangitis, and also a right liver abscess (S5/8), which required percutaneous drainage at 9 years after PPPD. At 16 years after PPPD, he had been admitted to the other hospital because of acute purulent cholangitis. Although medical treatment resolved the cholangitis, the patient was referred to our hospital because of dilatation of the intrahepatic biliary duct (B2). Peroral double-balloon enteroscopy revealed that the diameter of the hepaticojejunostomy anastomosis was 12 mm, and cholangiography detected intrahepatic stones. Lithotripsy was performed using a basket catheter. At 1 year after lithotripsy procedure, the patient is doing well. Hepatobiliary scintigraphy at 60 minutes after intravenous injection demonstrated that deposit of the tracer still remained in the upper afferent loop jejunum. Therefore, we considered that the recurrent cholangitis, liver abscess, and intrahepatic lithiasis have been caused by biliary stasis due to nonobstructive afferent loop syndrome. Biliary retention due to nonobstructive afferent loop syndrome may cause recurrent cholangitis or liver abscess after hepaticojejunostomy, and double-balloon enteroscopy and hepatobiliary scintigraphy are useful for the diagnosis of nonobstructive afferent loop syndrome.

show abstract

“…9 Kuni and associates 13 suggest that knowledge of the histopathological correlates of scintigraphic abnormalities could prove useful in differentiating rejection from other parenchymal pathologies in transplant recipients; however, other researchers found that scintigraphic differentiation between rejection and other parenchymal complications is difficult. 1,8,9,14,15 The present study evaluated the role of quantitative hepatobiliary scintigraphy in the diagnosis of parenchymal complications in postliver transplant recipients. Hepatocyte extraction fraction value and HPRI were used for quantitative analysis.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2014

Exp Clin Transplant

View full text Add to dashboard Cite

Objectives: The aim of this study was to evaluate the usefulness of the hepatic parenchymal retention index in the early diagnosis of parenchymal complications in liver transplant recipients as determined by hepatobiliary scintigraphy. Materials and Methods: This retrospective study reviewed 100 liver transplant recipients who had undergone orthotopic liver transplant. In all cases, hepatobiliary scintigraphy images recorded 7 to 10 days posttransplant were quantitatively reinterpreted according to hepatic parenchymal retention index. The hepatocyte extraction fraction value was also calculated. Scintigraphic findings as well as clinical, laboratory, and biopsy results were assessed. Results: Quantitative analysis showed normal hepatocyte extraction fraction value in all subjects. However, significant differences in hepatic parenchymal retention index were observed. Thus, subjects were divided into 3 groups: group 1 (n=75), normal; group 2 (n=15), severely elevated; group 3 (n=10), mildly-to-moderately elevated hepatic parenchymal retention index. Evaluation of histopathological, clinical, and laboratory findings showed normal grafts in all group 1 recipients, acute rejection in all group 2 recipients, and hepatocyte damage/intrahepatic cholestasis in all group 3 recipients. Conclusions: Based on these findings, we determined that hepatocyte extraction fraction value was not useful, whereas hepatic parenchymal retention index was beneficial for early and accurate diagnosis of parenchymal complications in liver transplant recipients.

show abstract

Hepatobiliary scintigraphy for the assessment of biliary stricture after pediatric living donor liver transplantation for hepaticojejunostomy reconstruction: The value of the excretion rate at 60 min

Cited by 5 publications

References 23 publications

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

Recurrent Cholangitis by Biliary Stasis Due to Non-Obstructive Afferent Loop Syndrome After Pylorus-Preserving Pancreatoduodenectomy: Report of a Case

Untitled

Contact Info

Product

Resources

About