Hepatocellular Adenoma and Nodular Regenerative Hyperplasia of the Liver in a Young Man

Nguyên, Toàn; Oakes, David D.; Fogel, Michael R.; Williams, Laura; Sherck, John P.; Kozar, Mark

doi:10.1097/00004836-198608000-00020

Cited by 9 publications

(2 citation statements)

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“…HCA is rare benign hepatic neoplasm usually associated with use of estrogen, anabolic steroids, metabolic disease or rarely vascular abnormality [2]. Combination of NRH with HCA occurring synchronously is extremely rare with occasional case report in literature [3,4] Here, we report unusual combination of NRH and HCA in a young female who succumbed to pulmonary hypertension (PH) and intrapulmonary haemorrhage.…”

Section: Introductionmentioning

confidence: 94%

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A Tale of Two Benign Hepatic Nodules with Pulmonary Hypertension

Raj¹,

Gadgil²,

Amarapurkar³

2020

J Gast Hepa Rep

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Nodular regenerative hyperplasia and hepatocellular adenoma are two benign liver lesions with low risk of malignant potential. Nodular regenerative hyperplasia appears to be result of adaptive reaction to hepatic vasculopathy. Hepatocellular adenoma is associated with use of estrogen, anabolic steroids, metabolic disease and rarely vascular abnormality. We report an unusual case of a young female who presented with progressive dyspnoea, cough and edema. She succumbed to her illness within two days of her hospital stay. A medical autopsy was performed which revealed hepatocellular adenoma arising on the background of nodular regenerative hyperplasia along with pulmonary hypertension and intrapulmonary hemorrhage. Unusual case of nodular regenerative hyperplasia and hepatocellular adenoma associated with pulmonary hypertension where vascular pathology is suggested as a common event in their pathogenesis. Hence, it is advisable to rule out associated conditions with the help of imaging techniques in patients with pulmonary hypertension.

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Section: Introductionmentioning

confidence: 94%

“…The stage at which both liver nodules appeared was not known. Coexistence of NRH with HCA is extremely rare with very few isolated case reports in literature [3,4]. HCA is known to occur in women of child bearing age and associated with use of estrogen, anabolic steroids, metabolic disease and rarely vascular abnormality [2].…”

Section: Introductionmentioning

confidence: 99%