Hepatocellular carcinoma in a free‐living marmoset (<i>Callithrix</i> sp.) with concomitant biliary trematodiasis

Díaz‐Delgado, Josué; Sanches, Tatiana; Santos-Cirqueira, Cinthya dos; Coimbra, Amanda Aparecida Cardoso; Guerra, Juliana Mariotti; Joppert, A.; Loretto, C. Di; Rizardi, M. B.; Sansone, Marcelo; Nagamori, Filipe Onishi; Gonçalves, Pedro; Réssio, Rodrigo Albergaria; Iglezias, Silvia D’Andretta; Fernandes, Natália Coelho Couto de Azevedo; Kanamura, Cristina; Groch, Kátia R.; Catão‐Dias, José Luiz

doi:10.1111/jmp.12329

Cited by 5 publications

(3 citation statements)

References 34 publications

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“… Callithrix sp . HCC 1 [ 229 ] Schistosoma mansoni Pan troglodytes HCC 1 [ 232 ] Taenia taeniformis Rattus norvegicus renal sarcoma 1 [ 52 ] Taenia taeniformis Rattus norvegicus hepatic sarcoma 1 [ 52 ] Taenia taeniformis Rattus norvegicus hepatic sarcoma 11 [ 241 ] Taenia taeniformis Rattus norvegicus hepatic fibroma 1 [ 241 ] Taenia taeniformis Rattus norvegicus hepatic sarcoma 3 [ 242 ] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma 16 [ 240 ] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma 1 [ 244 ] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma 2 [ 245 ] Taenia taeniformi...…”

Section: Parasites Associated With Neoplasia In Domestic and Wild Ani...mentioning

confidence: 99%

“…was recently observed in combination with Platynosomum sp . infection in Brazil [ 229 ]. Although a direct cause-effect link may be incidental, the authors could not rule out a potential primary or contributing oncogenic role of the parasite.…”

Section: Parasites Associated With Neoplasia In Domestic and Wild Ani...mentioning

confidence: 99%

“…Callithrix sp. HCC [229] Schistosoma mansoni Pan troglodytes HCC [232] Taenia taeniformis Rattus norvegicus renal sarcoma [52] Taenia taeniformis Rattus norvegicus hepatic sarcoma [52] Taenia taeniformis Rattus norvegicus hepatic sarcoma [241] Taenia taeniformis Rattus norvegicus hepatic fibroma [241] Taenia taeniformis Rattus norvegicus hepatic sarcoma [242] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma [240] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma [244] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma [245] Taenia taeniformis Rattus norvegicus hepatic sarcoma [247] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma [248] Taenia taeniformis Rattus norvegicus hepatic fibrosarcoma ND [249] Taenia taeniformis Rattus norvegicus hepatic fibroma [250] Taenia taeniformis Mus musculus hepatic fibrosarcoma [246] Taenia taeniformis Ondatra zibethicus hepatic fibrosarcoma [243] Arthropoda Linguatula serrata Canis lupus familiaris nasal basosquamous carcinoma [274] Apicomplexa Theileria annulata Bos taurus lymphoma [288] surface of the mouth, esophagus, rumen, and stomach of several birds and mammals are the locations where the adults reside and reproduce [47]. In 1907, when three wild rats were dissected, Danish physician Johannes Fibiger observed gastric tumors as well as roundworms inside them.…”

Section: Bos Taurus Leiomyoma [217]mentioning

confidence: 99%

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Cancerogenic parasites in veterinary medicine: a narrative literature review

Fonti

Parisi

Mancianti

et al. 2023

Infect Agents Cancer

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Parasite infection is one of the many environmental factors that can significantly contribute to carcinogenesis and is already known to be associated with a variety of malignancies in both human and veterinary medicine. However, the actual number of cancerogenic parasites and their relationship to tumor development is far from being fully understood, especially in veterinary medicine. Thus, the aim of this review is to investigate parasite-related cancers in domestic and wild animals and their burden in veterinary oncology. Spontaneous neoplasia with ascertained or putative parasite etiology in domestic and wild animals will be reviewed, and the multifarious mechanisms of protozoan and metazoan cancer induction will be discussed.

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Section: Parasites Associated With Neoplasia In Domestic and Wild Ani...mentioning

confidence: 99%

Section: Parasites Associated With Neoplasia In Domestic and Wild Ani...mentioning

confidence: 99%

Section: Bos Taurus Leiomyoma [217]mentioning

confidence: 99%

See 1 more Smart Citation

Cancerogenic parasites in veterinary medicine: a narrative literature review

Fonti

Parisi

Mancianti

et al. 2023

Infect Agents Cancer

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Common Marmosets

Hopper¹

2020

Handbook of Exotic Pet Medicine

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Hepatobiliary Platynosomosis in Black‐Tufted Marmosets (Callithrix penicillata): A Lethal Threat for Wildlife and Captive Populations

de Macêdo,

de Sousa,

Souza

et al. 2024

American J Primatol

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Helminthic infections, particularly those caused by trematodes, pose a significant health risk to both animals and humans. This study investigates hepatobiliary platynosomosis (HP) caused by Platynosomum illiciens in black‐tufted marmosets (Callithrix penicillata) in Central Brazil. Data were retrospectively collected from autopsy records at the Laboratory of Veterinary Pathology and Forensics, University of Brasília, from January 2006 to July 2021. Epidemiological, clinical, and pathological information was analyzed, including comparisons between free‐ranging and captive marmosets. A total of 1596 nonhuman primate (NHP) death records were examined, with black‐tufted marmosets accounting for 75.6% (1206/1595) of autopsies. HP was identified in 10.8% (131/1206) of these cases. Captive marmosets showed a higher prevalence of HP (49.6%) than free‐ranging ones (6.5%). This study revealed a significant seasonal trend, with higher HP prevalence observed during the wet season until the onset of the dry season. Pathological examinations revealed severe liver and bile duct damage in fatal HP cases, including fibrosis, bile duct thickening, and the presence of flukes. Captive marmosets exhibited pronounced clinical signs, such as weight loss and apathy. Morphological and molecular analysis of sampled flukes confirmed P. illiciens infecting the marmosets. These findings underscore the substantial impact of HP on marmoset populations, particularly in captive settings. The high lethality (58% overall; 81.6% in captivity) highlights the need for improved management and preventive measures in captive environments. This study contributes to understanding HP epidemiology, clinical manifestations, and pathological outcomes, underscoring the disease's significance for the health of both free‐ranging and captive NHP populations. Our findings also support the need to develop targeted strategies to mitigate the impact of HP on primate species populations.

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Hepatocellular carcinoma in a free‐living marmoset (Callithrix sp.) with concomitant biliary trematodiasis

Cited by 5 publications

References 34 publications

Cancerogenic parasites in veterinary medicine: a narrative literature review

Cancerogenic parasites in veterinary medicine: a narrative literature review

Common Marmosets

Hepatobiliary Platynosomosis in Black‐Tufted Marmosets (Callithrix penicillata): A Lethal Threat for Wildlife and Captive Populations

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