Hepatocyte Selection Medium

Tomizawa, M.; Shinozaki, Fuminobu; Motoyoshi, Takao Sugiyama Yasufumi; Yamamoto, Shozo; Sueishi, Makoto

doi:10.5772/58394

Cited by 1 publication

(1 citation statement)

References 39 publications

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“…[ 136,137 ] Several studies have shown that increase in the cell permeability mediated by ultrasound shares some similarities to those achieved via electroporation. [ 138,139 ]…”

Section: Macroengineered Intracellular Deliverymentioning

confidence: 99%

A Comprehensive Review on Intracellular Delivery

Rad

Bazaz

et al. 2021

Advanced Materials

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Intracellular delivery is considered an indispensable process for various studies, ranging from medical applications (cell‐based therapy) to fundamental (genome‐editing) and industrial (biomanufacture) approaches. Conventional macroscale delivery systems critically suffer from such issues as low cell viability, cytotoxicity, and inconsistent material delivery, which have opened up an interest in the development of more efficient intracellular delivery systems. In line with the advances in microfluidics and nanotechnology, intracellular delivery based on micro‐ and nanoengineered platforms has progressed rapidly and held great promises owing to their unique features. These approaches have been advanced to introduce a smorgasbord of diverse cargoes into various cell types with the maximum efficiency and the highest precision. This review differentiates macro‐, micro‐, and nanoengineered approaches for intracellular delivery. The macroengineered delivery platforms are first summarized and then each method is categorized based on whether it employs a carrier‐ or membrane‐disruption‐mediated mechanism to load cargoes inside the cells. Second, particular emphasis is placed on the micro‐ and nanoengineered advances in the delivery of biomolecules inside the cells. Furthermore, the applications and challenges of the established and emerging delivery approaches are summarized. The topic is concluded by evaluating the future perspective of intracellular delivery toward the micro‐ and nanoengineered approaches.

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“…[ 136,137 ] Several studies have shown that increase in the cell permeability mediated by ultrasound shares some similarities to those achieved via electroporation. [ 138,139 ]…”

Section: Macroengineered Intracellular Deliverymentioning

confidence: 99%

A Comprehensive Review on Intracellular Delivery

Rad

Bazaz

et al. 2021

Advanced Materials

View full text Add to dashboard Cite

show abstract

Hepatocyte Selection Medium

Cited by 1 publication

References 39 publications

A Comprehensive Review on Intracellular Delivery

A Comprehensive Review on Intracellular Delivery

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