Hepatoprotective Activity of <i>Haritaki</i> (<i>Terminalia chebula</i> Retz): A Systematic Review

Abstract

Terminalia chebula Retz, also referred as Haritaki in Sanskrit, is a widely available plant distributed all over India. T. chebula has been widely acknowledged for its therapeutic qualities and application in treating several kinds of diseases. This plant is part of the Combretaceae family and serves a crucial role in maintaining a disease-free community. The hepatoprotective qualities of T. chebula are widely recognized. Consequently, published literature from “Pubmed, Scopus, Cochrane database, Google Scholar” up to 2023 was used in a systematic review. With a computer-based search engine, 115 Studies in total were looked up. In the present study, T. chebula’s hepatoprotective properties were investigated using PubMed, Scopus, Cochrane and other resources. Twelve studies that met the requirements were chosen after screening. To identify the various activities, T. chebula plant leaves, fruits, roots, and polymer were examined. This systematic review aimed to collect and analyze data on the efficacy of T. chebula as a hepatoprotective treatment from clinical trials, in vivo investigations, and in vitro experiments. The 12 studies that were chosen had significantly different study designs and results. The study concludes that T. chebula provides alternatives for several medical disciplines due to its hepatoprotective and diseaseprevention qualities.