Hepatoprotective Effect of Curdrania tricuspidata Extracts against Oxidative Damage

Anti-Inflammatory and Gastroprotective Activities of C udrania Tricuspidata Leaf Extract Against Acute HCl/Ethanol-Induced Gastric Mucosal Injury in Sprague-Dawley Rats

“…We found in the previous study that polyphenol and flavonoid contents in CTL10 were 8.22 ± 0.12 and 3.23 ± 0.13 mg/g, respectively (Kim et al . ). In addition, a previous study by Lee et al .…”

“…; Kim et al . ). The genus Cudrania belongs to the family Moraceae and is mainly distributed in East Asian countries, such as China, Japan and Korea.…”

“…The presence of phenolic compounds possibly explains the inhibitory effect of CT extract on gastric inflammation induced by acute ethanol. In the previous study, we found that CT leave ethanol 10% extract (CTL10) has higher contents of polyphenol and flavonoid than CT leave water extract (Kim et al 2012). Therefore, in this study, we have investigated the inhibitory effect of CTL10 on ethanolinduced gastric inflammation, specifically on gastric juice secretion and ethanol-induced gastric mucosal damage in rats.…”

“…Most flavonoid protective mechanisms for gastric inflammation involve the radical-scavenging properties and inactivation of ROS (La Casa et al 2000;Kahraman et al 2003). Recently, there is increasing evidence that Cudrania tricuspidata (CT) can act as an efficient free radical scavenger, helping the antioxidant defense system Kim et al 2012). The genus Cudrania belongs to the family Moraceae and is mainly distributed in East Asian countries, such as China, Japan and Korea.…”

Topical Application of Cudrania tricuspidata Stem Extract Inhibits Atopic Dermatitis-Like Skin Lesions in an NC/Nga Mouse Model: An Experimental Animal Study

“…The selected natural material was extract of Cudrania tricuspidata (C. tricuspidata), a kind of mulberry tree which is native to East Asian countries such as Korea, China and Japan [4]- [7], and occurs mainly in the southern area of South Korea [5]. Extracts of the fruit, leaves, root-bark and stems of C. tricuspidata have been traditionally used for hepato-protection [8]- [10], and as anti-hypertension [11], anti-diabetes [12] [13], anti-allergy [14] and antioxidation [15]- [17] treatments in Korea. Well-known physiologically active compounds of C. tricuspidata are isoflavones and flavonoids from the fruits [18], gerontoxanthone, cudraflavone B, gericudranin, cudraxanthones, isocudraxanthones, some flavanones and macluraxanthone from the roots [9] [19], kaempferol and kaempferol-D-glucopyranoside from the leaves [20], and kaempferide-D-glucopyranoside and naringenin-D-glucopyranoside from the stems [21].…”