2020
DOI: 10.1080/01480545.2020.1772279
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Hepatoprotective effect of Raspberry ketone and white tea against acrylamide-induced toxicity in rats

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Cited by 22 publications
(16 citation statements)
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“…As mentioned above, Hamdy et al [63] confirmed that RK improves the SOD and CAT levels reduced by AA. In addition, RK treatment significantly decreased the plasma MDA level (Group IV, 13.18 ± 2.618 nmol/mL), which is increased by AA (Group II, 20.83 ± 1.83 nmol/mL).…”
Section: Lipid Peroxidationmentioning
confidence: 70%
See 1 more Smart Citation
“…As mentioned above, Hamdy et al [63] confirmed that RK improves the SOD and CAT levels reduced by AA. In addition, RK treatment significantly decreased the plasma MDA level (Group IV, 13.18 ± 2.618 nmol/mL), which is increased by AA (Group II, 20.83 ± 1.83 nmol/mL).…”
Section: Lipid Peroxidationmentioning
confidence: 70%
“…Hamdy et al [63] conducted a study to evaluate the hepatoprotective effect of raspberry ketones on the oxidative stress induced by acrylamide (AA) in rats. In this experiment, rats were allocated randomly into four groups: Group I (control group); Group II (toxicity induced by AA (5 mg/kg/day)); Group III (treated with RK alone (6 mg/kg/day)); Group IV (treated with both AA and RK).…”
Section: Antioxidant Enzyme Activitymentioning
confidence: 99%
“…The combination treatment of RK and white tea, after acrylamide-induced liver damage, showed a decrease in elevated liver enzymes such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP). Immuno-histological examination of rat livers showed a reduction in hepatic damage, measured as a decrease in necrotic changes and reduced inflammation and vacuolation [ 24 ].…”
Section: Potential Role Of Rk As a Hepatoprotectionmentioning
confidence: 99%
“…Raspberry ketone and white tea treatment also led to increased adiponectin levels and a decrease in caspase-3, an apoptosis marker level. Histopathological studies showed concurrent improvement in hepatic cell structure and function [ 24 ]. The CCL4-induced liver toxicity could be similarly reversed by RK treatment, thus strengthening the evidence for RK to be considered as a possible treatment for acute and chronic liver diseases.…”
Section: Potential Role Of Rk As a Hepatoprotectionmentioning
confidence: 99%
“…In addition, raspberry ketone is utilized as an attractant in insect baits (Perez 1983;Metcalf et al 1983;Deifel 1989) and as a component in perfumes (Dumont et al 1996;Farwick et al 2019), whereas further applications in cosmetic industry, e.g., as skin whitening or hair growth inducing agent, remain controversial (Harada et al 2008;Kim et al 2016). Other publications promote dose-dependent health benefits with regard to an anti-obese effect (Morimoto et al 2005;Park 2015;Tsai et al 2017;Zhao et al 2019;Mir et al 2019) or suggest medical applications due to its antioxidant and anti-inflammatory potential (Parmar and Tripathi 1991;Khan et al 2018;Fouad et al 2019;Mohamed et al 2020;Hamdy et al 2020).…”
Section: Introductionmentioning
confidence: 99%