Herbal-Based Dressings in Wound Management

Abstract

Wound management is one of the major globalchallenge in recent times and wound-associated infection hasa significant impact on the healthcare economy worldwide. Woundscan beacute or chronic type, also diabetic, trauma, accidental, burn woundsand minor cuts, bruises, and rashes,etc. One of theprimary treatment options available in these conditionsaretheuse of suitable dressing materials to cover the wound and acceleratethehealing process. Since ancienttimes, according to archaeological theories, medicinal plants and oils have been employed forthe treatment of wounds.Todayresearchers across the globe are focusing their efforts to fabricatenovel dressing materials that canprovide the most effective treatment, easy exchange of nutrients, and absorb exudate fromthe wounds. Very lately, various research groups are also concentrating on the design and development of herb-loaded wound dressings, asherbalpreparation contains numerousphytoconstituents with a broad spectrum of pharmacological properties when compared to synthetic drugs and also due to the perceived notion that herbal products are generally safe, even when administered over prolonged periods. As they contain numerous bioactives,that can act onthe various phases of the wound healing process, providing anideal environmentfor the healing process. The present review discusses the numerous approaches that are employed for the preparationofdressing materials incorporated with plant-derived phytoconstituents/extracts. This review also provides an insight into the healing process and wound healing agents derived from medicinal plants and oils.The review can serve as a database for researchers working in this field and can help them to select the most appropriate dressing material for the effective delivery of herbal preparations inthe management of wounds.

The wound healing effect of polycaprolactone-chitosan scaffold coated with a gel containing Zataria multiflora Boiss. volatile oil nanoemulsions

“…On the other hand, applications of sustained drug delivery systems in regenerative medicine, especially in wound healing, have increased drastically [33][34][35][36]. Meanwhile, the use of herbal medicinal extracts in wound healing has attracted the attention of many researchers due to its advantages, such as few side effects, ease of extraction, and reasonable price [37,38]. Amongst, Zataria Multiflora Boiss (ZM), called in Persian "Shirazi thyme", has anti-inflammatory, antioxidant, and immunomodulatory effects, making it a suitable option for use in wound healing scaffolds [39][40][41].…”