Herbal formula MaZiRenWan (Hemp Seed Pill) for constipation: A systematic review with meta-analysis

Yang, Mingxiao; Feng, Yang; Zhang, Yi Lily; Smith, Colleen M.; Hou, Yen-Nien; Wang, Hui; Deng, Gary; Mao, Jun J.

doi:10.1016/j.phymed.2021.153459

Cited by 7 publications

(6 citation statements)

References 30 publications

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“…Memorial Sloan Kettering Cancer Center's Herbal Education and Research in Oncology program focuses on synthesizing the evidence base of TCM herbs to inform clinical research, education, and practice 123 . The initiative promotes bidirectional learning with Chinese experts to share their knowledge and experience in incorporating TCM approaches in cancer care while the US team trains Chinese physician‐scientists on literature review, data analysis, protocol design, and scientific writing in China 224‐228 . The University of Texas MD Anderson Cancer Center and its sister institutions have facilitated the documentation of TCIM use in patients with cancer in South America 62 .…”

Section: Challenges and Opportunities In Researchmentioning

confidence: 99%

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Mao

Pillai

Andrade

et al. 2021

CA A Cancer J Clinicians

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232

103

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The increase in cancer incidence and mortality is challenging current cancer care delivery globally, disproportionally affecting low‐ and middle‐income countries (LMICs) when it comes to receiving evidence‐based cancer prevention, treatment, and palliative and survivorship care. Patients in LMICs often rely on traditional, complementary, and integrative medicine (TCIM) that is more familiar, less costly, and widely available. However, spheres of influence and tensions between conventional medicine and TCIM can further disrupt efforts in evidence‐based cancer care. Integrative oncology provides a framework to research and integrate safe, effective TCIM alongside conventional cancer treatment and can help bridge health care gaps in delivering evidence‐informed, patient‐centered care. This growing field uses lifestyle modifications, mind and body therapies (eg, acupuncture, massage, meditation, and yoga), and natural products to improve symptom management and quality of life among patients with cancer. On the basis of this review of the global challenges of cancer control and the current status of integrative oncology, the authors recommend: 1) educating and integrating TCIM providers into the cancer control workforce to promote risk reduction and culturally salient healthy life styles; 2) developing and testing TCIM interventions to address cancer symptoms or treatment‐related adverse effects (eg, pain, insomnia, fatigue); and 3) disseminating and implementing evidence‐based TCIM interventions as part of comprehensive palliative and survivorship care so patients from all cultures can live with or beyond cancer with respect, dignity, and vitality. With conventional medicine and TCIM united under a cohesive framework, integrative oncology may provide citizens of the world with access to safe, effective, evidence‐informed, and culturally sensitive cancer care.

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Section: Challenges and Opportunities In Researchmentioning

confidence: 99%

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Mao

Pillai

Andrade

et al. 2021

CA A Cancer J Clinicians

Self Cite

232

103

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“…Mashiningan contains six herbs, including Cannabis Fructus, Rhei Rhizoma, Aurantii Fructus Immaturus, Armeniacae Semen, Magnoliae Cortex, and Paeoniae Radix. A doubleblinded randomized control study conducted in 2011 [44] and a meta-analysis [45] confirmed the efficacy of mashiningan as a purgative. Mashiningan is often used by older people since a single dose contains only 1.3 g of Rhei Rhizoma extract, which renders it suitable for frail old individuals.…”

Section: Mashiningan (麻子仁丸)mentioning

confidence: 86%

Kampo Medicine for Older People: A Review

Nogami¹,

Arai²,

Iwasaki³

2022

OBM Geriatr

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Several countries have entered the super-aging era. In Japan, the recently reported average life expectancy is approximately 90 years. Kampo medicine (a form of traditional Japanese medicine) is a part of the official medical service in Japan and is widely used for treating various illnesses of older people. However, although general physicians often prescribe Kampo preparations, most Japanese general physicians do not have an intimate understanding of the iatrology of Kampo. Kampo is based on traditional Chinese medicine modified according to the Japanese environment, characteristics, and society. Although Kampo prescriptions are beneficial in geriatric medicine, they were initially developed and applied according to the medical principles of traditional Japanese and Chinese medicine. Moreover, improper administration of these traditional preparations can lead to severe adverse consequences. In this review, we have described the efficacy of Kampo medicine for geriatric syndromes and the traditional meanings and rules underlying Kampo prescriptions.

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“…In collaboration with the MSK Pharmacy department, IMS established an herbal formulary and dispensary to offer patients quality-controlled traditional Chinese medicine (TCM) herbal formulas with evidence of empirical use, safety, and preliminary efficacy for mood [ 16 ], insomnia [ 17 ], and gastrointestinal issues such as constipation or diarrhea [ 18 , 19 ], which are frequently encountered in oncology settings. This herbal formulary was prepared after careful discussions among experienced integrative medicine physicians on common, challenging symptoms encountered in our practice, where conventional medications do not meet the needs of some patients.…”

Section: Methodsmentioning

confidence: 99%

“…This herbal formulary was prepared after careful discussions among experienced integrative medicine physicians on common, challenging symptoms encountered in our practice, where conventional medications do not meet the needs of some patients. In addition, we reviewed classic herbal medicine textbooks, conducted systematic reviews of the available literature [ 18 – 20 ], and had extensive discussions with TCM oncologists in China, where TCM herbs and formulas are commonly used to treat common cancer-related symptoms and sequelae associated with treatments [ 21 ].…”

Section: Methodsmentioning

confidence: 99%

Integrating herbal medicine into oncology care delivery: development, implementation, and evaluation of a novel program

Hou

Chimonas

Gubili

et al. 2023

Support Care Cancer

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Objective To evaluate the feasibility of a novel program facilitating patient-provider communication about appropriate use of herbal medicine at a large academic cancer center and its impact on patient wellbeing. Methods In the Herbal Oncology Program (HOP), integrative medicine providers counseled patients about unmet symptom needs and prescribed traditional Chinese medicine (TCM) herbs when indicated, taking into consideration the clinical context, patient preference, and research evidence. To evaluate the feasibility and outcomes, we performed a retrospective analysis using medical record data (symptoms and other concerns that motivated patients to seek herbal products, types and numbers of dispensed TCM herbs, and demographic characteristics). We also conducted a survey to assess patient experience and satisfaction. Results All 851 participants were outpatients, with 712 (84%) in active treatment. HOP dispensed 1266 herbal prescriptions for a range of symptoms, most commonly GI symptoms (467, 37%); pain (353, 28%); and treatment-related fatigue, sleep, and mood disorders (346, 27%). Of 269 patients invited to the survey, 107 (40%) completed it. A majority of respondents 70.9% (73/103) were satisfied with the effectiveness of dispensed herbs in relieving their symptoms, and few 6.7% (7/104) had experienced mild adverse events that resolved after discontinuing herbal use. Conclusions The study’s findings support the feasibility of integrating herbal medicine into an academic oncology setting. Patient satisfaction with HOP was high, with limited adverse events. The patterns of herbal prescriptions in HOP suggest future areas for clinical research to strengthen the evidence base around safe and effective use.

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Herbal formula MaZiRenWan (Hemp Seed Pill) for constipation: A systematic review with meta-analysis

Cited by 7 publications

References 30 publications

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Kampo Medicine for Older People: A Review

Integrating herbal medicine into oncology care delivery: development, implementation, and evaluation of a novel program

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