Herbal medicine in Jordan with special emphasis on less commonly used medicinal herbs

Afifi, Fatma U.; Abu‐Irmaileh, Bashaer

doi:10.1016/s0378-8741(00)00215-4

Cited by 112 publications

(57 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is necessary since all Achillea species were referred to locally in Jordan as "Qaysoum" and recommended for a big variety of diseases despite differences they exhibited in scientific evaluation [36]. A. fragrantissima extracts should be further evaluated as for their potential use in preventing/treating diseases in which oxidative stress is a part of the pathophysiology.…”

Section: Resultsmentioning

confidence: 99%

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

Hammad¹,

Matar²,

Liţescu³

et al. 2014

View full text Add to dashboard Cite

Aqueous and hydro-alcoholic extracts of Achillea fragrantissima L. (Asteraceae) grown in Jordan were screened for their antioxidant, antimicrobial, antiplatelet, anti-proliferative and acetylcholinesterase (AChE) inhibition efficacy. Total phenols and flavonoids were determined colorimetrically. The radical scavenging activities were evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical scavenging activity assays. High performance liquid chromatography-mass spectrometry (HPLC-MS) analysis resulted in the identification of 7 phenolic compounds in the hydro-alcoholic extract and 4 compounds in the aqueous extract; quercetin 3-β-D-glucoside was the main component for both extracts. Antimicrobial activities were determined by antimicrobial susceptibility testing such as agar well-diffusion method, minimum inhibition concentration and minimum bactericidal concentration. Gram positive bacteria showed sensitivity to hydro-alcoholic extract in the agar-well diffusion test. No significant activity was observed against gram negative bacteria and Candida albicans. Hydro-alcoholic extract had a bactericidal activity against Streptococcus pneumoniae and Bacillus cereus at high concentrations (MIC 12.5 mg/ml) rather than inhibitory effect. In vitro antiplatelet activity was tested on human whole blood using an electrical impedance method. At concentrations (50, 100, and 200 μg/ml), no effect on platelet aggregation was noticed. Anti-proliferative activity was investigated using the MTT assay. At concentrations up to 200 μg/ml, extracts did not possess cytotoxic activity against the MCF-7 cells. Acetylcholinesterase (AChE) inhibitory capacity of A. fragrantissima extracts was tested using TLC assay method, and neither aqueous, nor hydroalcoholic extracts showed AChE inhibition. The present investigation supported the traditional use of A. fragrantissima in the Jordanian folk medicine as an antimicrobial active representative of the genus Achillea. A. fragrantissima extracts should be further studied for their potential use in preventing/treating diseases in which oxidative stress is a part of the pathophysiology.

show abstract

Section: Resultsmentioning

confidence: 99%

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

Hammad¹,

Matar²,

Liţescu³

et al. 2014

View full text Add to dashboard Cite

show abstract

“…This plant is also commonly known in Roman as Nettle and in Jordan as Qurraus [1,2] . For decades, crude extracts of plant species of U. pilulifera have long been used in many countries around the world as a traditional medicine for the treatment of various diseases including Diabetes Mellitus (DM) [3,4] .…”

Section: Introductionmentioning

confidence: 99%

Effects of Leaf Extract of Urtica pilulifera L. on Male Reproductive System of Streptozotocin-Diabetic Rats

Irshaid¹,

Mm²

2009

American J. of Pharmacology and Toxicology

View full text Add to dashboard Cite

Problem statement: Urtica pilulifera L. (Urticaceae), has long been used for the treatment of various aliments including diabetes. Diabetes is a metabolic disorder characterized by hyperglycemia which has a deleterious effect on all systems including reproductive system of animals. Therefore, the current study was designed to investigate the effects of Urtica pilulifera on the reproductive system of diabetic rats. Approach: Forty male rats were evenly divided into four groups: Group I consisted of non-diabetic rats that received only the vehicle; group II-IV was injected intraperitonially with a single dose of streptozotocin (STZ) of 70 mg kg; groups III and IV were given methanol extract of Urtica pilulifera orally, 3 days after the STZ injection, at daily doses of 1.0 and 2.0 g kg −1 , respectively. After 4 weeks of treatments, all the rats were sacrificed. Results: Administration of 70 mg kg −1 of streptozotocin to male rats induced diabetes and significantly reduced the body and sex organ weights, testosterone levels, sperm count and motility and significantly increased the glucose levels and water and food intake. By contrast, rats given the Uritica pilulifera methanol extract had significantly improved body weight gain, whereas the glucose levels, water and food intake significantly improved in treated diabetic male rats. In addition, this extract improved the reproductive system of the diabetic male rats by significantly increasing the testis and epididymis weights, testosterone levels, sperm count and motility. Conclusion/Recommendations: We concluded that the adverse effects of STZ-diabetes on reproductive system of male rats can be reversed by treatment with Urtica pilulifera leaf extract; and this leaf extract exhibits antihyperglycemic and spermatogenic activities. Based on these findings, we suggested the possible utilization of Urtica pilulifera extracted as a therapy to prevent the development of diabetes in later life and improved the performance of male reproductive system in animals and humans.

show abstract

“…Ferula persica is a member of the genus Ferula, which can be found throughout central Asia, especially in Iran. In folk medicine, F. persica root is used for the treatment of diabetes (8). The present study evaluated the potential antimicrobial effects of F. persica gum extract, gold nanoparticles, and the synergy of both on metallo-beta-lactamase producing P. aeruginosa strains isolated from burn wound infections.…”

Section: Discussionmentioning

confidence: 99%

“…Ferula persica is a member of the genus Ferula, which can be found throughout central Asia, especially in Iran. In folk medicine, the roots of F. persica are used in the treatment of diabetes (8). Moreover, the anti-microbial activity of Ferula extract has been also reported (9).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Effects of Ferula persica Gum Extract and Gold Nanoparticles on Pseudomonas aeruginosa

Nejad¹,

Bamzadeh²,

Hejazi³

2016

Avicenna J Clin Microbiol Infect

View full text Add to dashboard Cite

Background: In the treatment of bacterial infections, drug resistance is a global problem; Pseudomonas aeruginosa is no exception. This bacterium is among the important causes of nosocomial infections, especially burn wound infections, and it is resistant to most applicable antibiotics. Objectives: The present study aimed to evaluate the anti-bacterial effects of Ferula persica gum extract and gold nanoparticles on P. aeruginosa strains isolated from burn wound infections in Isfahan in 2012. Materials and Methods: In this experimental study, 150 P. aeruginosa strains carrying the blaSPM-1 gene were isolated from burn wound infections and were confirmed by biochemical tests. The anti-microbial activities of Ferula persica gum extract and gold nanoparticles were evaluated by agar well-diffusion assay and microdilution antimicrobial susceptibility tests. The results were compared to ciprofloxacin. Results: The highest mean zone of inhibition (18 mm) was observed in a concentration of 250 mg/mL of F. persica extract, which was equal to that of ciprofloxacin. In the gold nanoparticles, the highest mean growth inhibition zone (10.18 mm) was observed in the dilution of 50 ppm. The highest zone of inhibition of nanoparticle-extract synergy was observed in the dilution of 125 mg/mL

show abstract

Herbal medicine in Jordan with special emphasis on less commonly used medicinal herbs

Cited by 112 publications

References 4 publications

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

Effects of Leaf Extract of Urtica pilulifera L. on Male Reproductive System of Streptozotocin-Diabetic Rats

Antimicrobial Effects of Ferula persica Gum Extract and Gold Nanoparticles on Pseudomonas aeruginosa

Contact Info

Product

Resources

About

Herbal medicine in Jordan with special emphasis on less commonly used medicinal herbs

Cited by 112 publications

References 4 publications

Biological activities of the hydro-alcoholic and aqueous extracts of &lt;i&gt;Achillea fragrantissima&lt;/i&gt; (Forssk.) grown in Jordan

Biological activities of the hydro-alcoholic and aqueous extracts of &lt;i&gt;Achillea fragrantissima&lt;/i&gt; (Forssk.) grown in Jordan

Effects of Leaf Extract of Urtica pilulifera L. on Male Reproductive System of Streptozotocin-Diabetic Rats

Antimicrobial Effects of Ferula persica Gum Extract and Gold Nanoparticles on Pseudomonas aeruginosa

Contact Info

Product

Resources

About

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan