Herbal Medicines for Treatment of Radiodermatitis: A Systematic Review and Meta-Analysis

Heydarirad, Ghazaleh; Ahadi, Bahareh; Vardanjani, Hossein Molavi; Cramer, Holger; Pasalar, Mehdi

doi:10.1089/acm.2021.0166

Cited by 8 publications

(4 citation statements)

References 22 publications

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“…A recent meta-analysis of 16 randomized controlled trials found that no herbal treatments to date are effective in the treatment of RD, including the very commonly used aloe vera. 12…”

Section: Resultsmentioning

confidence: 99%

“…A recent meta-analysis of 16 randomized controlled trials found that no herbal treatments to date are effective in the treatment of RD, including the very commonly used aloe vera. 12 While these treatments may not cure RD, they have been effective in alleviating some symptoms when used prophylactically. For example, use of epigallocatechin-3-gallate, a topical catechin, on breast cancer patients before chest wall radiation significantly decreased symptoms like burning, itching, and tenderness.…”

Section: Herbal Treatmentsmentioning

confidence: 99%

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Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

Simman

Bach

Abbas

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Background: Although radiation therapy remains an integral component in cancer treatment, the sequela of tissue damage can result in long-term morbidity and mortality for patients. This article aimed to perform a comprehensive review of the current literature for both nonsurgical and surgical management strategies for radiation-induced injuries. Methods: A literature search was performed on PubMed to review the current described management and treatment options for radiation-induced injuries. Patient demographics, medical diagnoses, complications, strategies of management care, and outcomes were reviewed. Results: The most commonly described management options and reconstructive techniques of radiation wounds were analyzed and reported. Conclusions: Consideration of current techniques and outcomes in the management of radiation-induced wounds demonstrates that impaired wound healing remains a major problem. This literature review provides a detailed overview of the most frequently used therapies with recommendations for surgeons.

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“…A recent meta-analysis of 16 randomized controlled trials found that no herbal treatments to date are effective in the treatment of RD, including the very commonly used aloe vera. 12…”

Section: Resultsmentioning

confidence: 99%

Section: Herbal Treatmentsmentioning

confidence: 99%

Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

Simman

Bach

Abbas

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Section: Scopementioning

confidence: 99%

“…The first attempt to gather all the information concerning the application and the role of herbal extracts in prevention and treatment of radiodermatitis was carried out by Kalekhan et al [57] and Heydariard et al [58]. Heydariard and co-workers [58] focused on collecting data from randomized control trials, which compared herbal compounds against a standard medication or placebo treatment or prevention of radiodermatitis. Five dimensions were evaluated: bias related to the errors in the randomization process, bias due to not receiving the desired treatment, bias due to missing data related to the outcome, bias in evaluating and measuring the outcome variables and incomplete or selective reporting outcomes.…”

Section: Scopementioning

confidence: 99%

Plant and Herbal Extracts as Ingredients of Topical Agents in the Prevention and Treatment Radiodermatitis: A Systematic Literature Review

Kulawik‐Pióro

Goździcka

2022

Cosmetics

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Background: The use of herbal extracts as the source of antioxidant substances capable of neutralizing free radicals and providing protection from ionizing radiation appears to be an alternative therapy for radiodermatitis. As concerns the prevention and treatment of side effects, a lot of recommendations are based on proper experience of radiotherapy centers. We summarize recent research aiming at reducing radiation-induced skin injuries by use of proper skin care, using topical preparations with herbal extracts including onco-cosmetics. Methods: This article is limited to a critical analysis of scientific and professional literature. It concerns preparations in different physicochemical forms, e.g., gels, emulsions, ointments. We stress the connection between the type of applied skin care (type of preparation, its composition, the dose), the properties of the herbal extract and the evaluation of its efficiency in preventing and treating radiation reaction on skin. Conclusions: Herbal extracts can be added to recipes because they are part of a category of cosmeceutical supplements and can be introduced into preparations without prescription. The effectiveness evaluation for herbal extracts in radiotherapy is not an easy task since there are no strict guidelines. Studies should be preceded by the analysis of herbal extracts and recipe in terms of physicochemical, dermatological and performance characteristics.

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Hübner

2024

Komplementäre Onkologie

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Herbal Medicines for Treatment of Radiodermatitis: A Systematic Review and Meta-Analysis

Cited by 8 publications

References 22 publications

Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

Plant and Herbal Extracts as Ingredients of Topical Agents in the Prevention and Treatment Radiodermatitis: A Systematic Literature Review

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