Herbal therapy associated with antibiotic therapy: potentiation of the antibiotic activity against methicillin – resistant Staphylococcus aureus by Turnera ulmifolia L

Abstract

Background: Staphylococcus genus is widely spread in nature being part of the indigenous microbiota of skin and mucosa of animal and birds. Some Staphylococcus species are frequently recognized as etiological agents of many animal and human opportunistic infections This is the first report testing the antibiotic resistance-modifying activity of Turnera ulmifolia against methicillinresistant Staphylococcus aureus -MRSA strain.

Yellow colored blooms of Argemone mexicana and Turnera ulmifolia mediated synthesis of silver nanoparticles and study of their antibacterial and antioxidant activity

“…The plant has medicinal uses such as to treat constipation, diarrhea, cold, flu, and circulatory problems. The laboratory evidence proposes that T. ulmifolia concentrate may increase action of antibiotics in aid of methicillin resistant S. aureus (Coutinho et al 2009). …”

Modulación de la resistencia a norfloxacina de Staphylococcus aureus por Croton A. campestris y Ocimum gratissimum L.

“…With the increase in the incidence of resistance to antibiotics, alternative natural products of plants could be of interest (1). Some plant extracts and phytochemicals are known to have antimicrobial properties, which could be of great importance in the therapeutic treatments.…”

“…Various chemical compounds, synthetic or from natural sources, have direct activity against many species of bacteria, enhancing the activity of a specific antibiotic, reversing the natural resistance of bacteria to specific antibiotics, causing the elimination of plasmids and inhibiting the active efflux of antibiotics through the plasma membrane (4). The potentiation of antibiotic activity or the reversal of antibiotic resistance allows the classification of these compounds as modifiers of antibiotic activity (1,4). Tables 2 and 3 show the phytochemical screening and the antibacterial activity of the methanol and hexane extracts, respectively.…”

“…The interference with bacterial enzyme systems can also be a potential mechanism of action (29). These mechanisms of action can be obtained by the combination of antibiotic with extract at a subinhibitory concentration applied directly to the culture medium (1,4).…”

Formulation and Evaluation of Therapeutic Potential of Nanoemulsion of a Blend of Antimicrobial Oils

“…1 Possible solutions may lie in the use of herbs or their products. 2 There have been reports of synergism among herbal products 3 and some natural oils derived from plants possess antimicrobial properties. The oils of Mentha piperita (peppermint), 4 Cymbopogon citratus (lemon grass) 5,6 and Eucalyptus 7,8 have been reported to possess antibacterial, antiviral and antifungal properties.…”