Herbicides in Camps Bay (Cape Town, South Africa), supplemented

Ojemaye, Cecilia Y.; Onwordi, C. T.; Pampanin, Daniela M.; Sydnes, Magne O.; Petrik, Leslie

doi:10.1016/j.scitotenv.2021.146057

Cited by 4 publications

(4 citation statements)

References 37 publications

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“…Pesticides comprise semi-volatile persistent organic pollutants (POPs), categorized by their use as biocides, fungicides, bactericides, insecticides, and herbicides [26,27,77]. Generally, a pesticide is defined as "any substance or combination of substances that is used to prevent or eradicate undesirable insects, including vectors of disease in animals, weeds, fungi, or other organisms in order to enhance food production, and to facilitate the processing, storage, transportation, or marketing of food and agricultural commodities" [78].…”

Section: Pesticidesmentioning

confidence: 99%

“…Irrespective of whether they are applied intentionally or by runoff, pesticides remain in various water sources for a long time due to their chemical properties such as adsorption and solubility [82]. In general, most herbicide monitoring studies are focused on surface freshwater sources such as lakes, rivers, and reservoirs, with a particular focus on organochlorine and organophosphorus compounds [26,27,77,79].…”

Section: Pesticidesmentioning

confidence: 99%

“…Consumption of animals exposed directly to such contaminants is becoming increasingly problematic [19]. Ojemaye and Petrik [26][27][28] reported that the levels of contaminants found in seawater, sediment, and several marine organisms (seaweed, invertebrates, and fish) may pose a threat to various trophic levels due to their high bioaccumulation factors and calculated risk quotients.…”

Section: Introductionmentioning

confidence: 99%

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Contaminants of Emerging Concern (CECs) and Male Reproductive Health: Challenging the Future with a Double-Edged Sword

Marcu

Keyser

Petrik

et al. 2023

Toxics

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Approximately 9% of couples are infertile, with half of these cases relating to male factors. While many cases of male infertility are associated with genetic and lifestyle factors, approximately 30% of cases are still idiopathic. Contaminants of emerging concern (CECs) denote substances identified in the environment for the first time or detected at low concentrations during water quality analysis. Since CEC production and use have increased in recent decades, CECs are now ubiquitous in surface and groundwater. CECs are increasingly observed in human tissues, and parallel reports indicate that semen quality is continuously declining, supporting the notion that CECs may play a role in infertility. This narrative review focuses on several CECs (including pesticides and pharmaceuticals) detected in the nearshore marine environment of False Bay, Cape Town, South Africa, and deliberates their potential effects on male fertility and the offspring of exposed parents, as well as the use of spermatozoa in toxicological studies. Collective findings report that chronic in vivo exposure to pesticides, including atrazine, simazine, and chlorpyrifos, is likely to be detrimental to the reproduction of many organisms, as well as to sperm performance in vitro. Similarly, exposure to pharmaceuticals such as diclofenac and naproxen impairs sperm motility both in vivo and in vitro. These contaminants are also likely to play a key role in health and disease in offspring sired by parents exposed to CECs. On the other side of the double-edged sword, we propose that due to its sensitivity to environmental conditions, spermatozoa could be used as a bioindicator in eco- and repro-toxicology studies.

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Section: Pesticidesmentioning

confidence: 99%

Section: Pesticidesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Contaminants of Emerging Concern (CECs) and Male Reproductive Health: Challenging the Future with a Double-Edged Sword

Marcu

Keyser

Petrik

et al. 2023

Toxics

Self Cite

View full text Add to dashboard Cite

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“…Pesticides comprise semi-volatile persistent organic pollutants, categorized by their use as biocides, fungicides, bactericides, insecticides, and herbicides ( 130 , 131 ). These pesticides have been widely used due to the increasing global population and the accompanying demand for larger food supplies.…”

Section: Introductionmentioning

confidence: 99%

The adverse role of endocrine disrupting chemicals in the reproductive system

Pan,

Liu,

et al. 2024

Front. Endocrinol.

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Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful substances in the environment. Endocrine disrupting chemicals (EDCs), characterized by hormone-like effects, have a wide range of influences on the reproductive system. EDCs are ubiquitous in the natural environment and are present in a wide range of industrial and everyday products. Currently, thousands of chemicals have been reported to exhibit endocrine effects, and this number is likely to increase as the testing for potential EDCs has not been consistently required, and obtaining data has been limited, partly due to the long latency of many diseases. The ability to avoid exposure to EDCs, especially those of artificially synthesized origin, is increasingly challenging. While EDCs can be divided into persistent and non-persistent depending on their degree of degradation, due to the recent uptick in research studies in this area, we have chosen to focus on the research pertaining to the detrimental effects on reproductive health of exposure to several EDCs that are widely encountered in daily life over the past six years, specifically bisphenol A (BPA), phthalates (PAEs), polychlorinated biphenyls (PCBs), parabens, pesticides, heavy metals, and so on. By focusing on the impact of EDCs on the hypothalamic-pituitary-gonadal (HPG) axis, which leads to the occurrence and development of reproductive system diseases, this review aims to provide new insights into the molecular mechanisms of EDCs’ damage to human health and to encourage further in-depth research to clarify the potentially harmful effects of EDC exposure through various other mechanisms. Ultimately, it offers a scientific basis to enhance EDCs risk management, an endeavor of significant scientific and societal importance for safeguarding reproductive health.

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