Hereditary angioneurotic edema and HLA types in two Danish families

Abstract

HLA types were determined in 19 patients and 9 healthy members of 2 Danish families with hereditary angioneurotic edema. The study revealed no connections between hereditary angioneurotic edema and the HLA system.

Comment on “Intensifying Weathering and Land Use in Iron Age Central Africa”

“…In Bas-Congo of the Democratic Republic of Congo and the Sangha region of the Republic of Congo, iron production appears even later, around 2000 yr B.P. ( 7 , 8 , 13 ), thus excluding any temporal correlation between increased Al/K values in the Atlantic around 2400 yr B.P. and potential deforestation for metallurgy on the continent.…”

“…and in the Democratic Republic of Congo (Congo-Kinshasa) (around 2400 yr B.P.) ( 7 – 9 ). The discrepancy between the timing of the localization of settlements and large-scale vegetation changes strongly suggests that human impact was not the major causal factor for forest disturbance.…”

“…People collected fruits and firewood near settlements and changed the species composition of the forest through some form of management. Archaeobotanical samples indicate a mosaic of mature and secondary forests, comprised of shade-tolerant and light-demanding trees, around the settlements ( 5 , 7 , 11 ). If agricultural plots were present, they must have been small.…”

Hereditary angio-oedema in Denmark: a nationwide survey

“…In the following years more cases of angioneurotic skin oedema were published in the Danish language but wrongly interpreted as uric acid diathesis 8,9 . In subsequent publications 10–16 three different families from Denmark with HAE were described, which is a small country with 5·4 million inhabitants. The pathophysiological basis of HAE was unravelled in the early 1960s 17,18 and the first Danish family had the diagnosis confirmed biochemically in 1970.…”