Hereditary Nonsyndromic Gingival Fibromatosis: Report of Family Case Series

Abstract

Hereditary gingival fibromatosis (HGF) is a rare, benign disorder with slowly progressive enlargement of maxillary and mandibular gingiva. Herewith, we report the first case series of HGF presenting among mother and all of her 3 children. Their complaints included unaesthetic appearance due to gingival growth, malocclusion, and difficulty in mastication. Conventional gingivectomy with oral hygiene measures and regular followup is the treatment of choice for such presentation.

Surgical Management of Generalized Gingival Enlargement – A Case Series

“…Only three case series (one containing three cases and two of four cases) have been reported till now and these studies contain both localized and generalized gingival enlargement cases. 8,11,14 To the best of our knowledge, the current study presents the largest case series of sixteen patients of different types of gingival enlargement. Moreover, this case series is about the cases of generalized gingival enlargement only and not the localized gingival enlargement.…”

“…The possible reasons for this could be the lack of information of the study population about their disease, delay in referral by the primary dental health care professionals, painless and benign slow growing nature of the problem. 14,18,26 Moreover; it takes much time for the gingival enlargement to cause aesthetic and functional problems significant for the patients to seek treatment. There is relatively very low incidence of inflammatory enlargement in the current study.…”

Idiopathic pigmented gingival fibromatosis: A case report

“…Gingival fibromatosis can present in two forms, a nodular form affecting the dental papillae or a symmetric uniform gingival enlargement. The enlarged tissues can partially or totally cover the crowns, cause diastemas and pseudopockets, delay tooth eruption, and malocclusion [3]. Recently, a mutation in the SOS-1 gene has been held responsible for this rare hereditary condition.…”

“…Idiopathic gingival fibromatosis is a gradually progressive benign enlargement that affects the marginal gingiva, attached gingival, and interdental papilla [2]. The gingival enlargement does not occur until the eruption of the primary or permanent dentition [3]. The gingival fibromatosis has a variable clinical presentation.…”