Heritability of anterior and posterior visual N1

Smit, Dirk J.A.; Posthuma, Daniëlle; Boomsma, Dorret I.; Geus, Eco J. C. de

doi:10.1016/j.ijpsycho.2007.06.005

Cited by 13 publications

(17 citation statements)

References 45 publications

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“…The N1 amplitude has been shown to depend on emotional arousal and emotional load of stimuli (Carretié et al 2004, Foti et al 2009), and on hereditary factors as well (Smit et al 2007). In the surface maps the amplitude of N1 wave, measured after the non-target and feedback stimuli, was higher in the occipital leads in patients with anxiety disorders.…”

Section: Discussionmentioning

confidence: 99%

EEG source activity during processing of neutral stimuli in subjects with anxiety disorders

Gmaj¹,

Januszko²,

Kamiński³

et al. 2016

Acta Neurobiologiae Experimentalis

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Anxiety disorders are a social problem due to their prevalence and consequences. It is crucial to explore the influence of anxiety on cognitive processes. In this study we recorded EEG activity from 73 subjects (35 patients, 38 controls, matched for age and education) during performance of the Continuous Attention Task. We used low resolution electromagnetic tomography (LORETA) for evaluation of mechanisms of impaired cognitive performance in anxiety disorders. Analysis showed that patients with anxiety disorders committed more errors than the controls, had a short latency of P300 and higher amplitude of ERPs at all steps of stimulus processing. Furthermore, we showed that there was a relationship between the scores of Hamilton Anxiety Scale and Beck Depression Inventory, and amplitudes and latencies of ERPs. The results of LORETA analysis showed that enhanced neural responses were found within circuits mediating visual information processing, sustained attention and anxiety. Also, we found higher current density within areas playing an important role in the brain fear network -anterior cingulate and anterior part of insula. Electrophysiological neuroimaging showed greater recruitment of cognitive resources in anxiety disorders, evidenced by higher current density and activation of greater number of brain areas. Despite the strategy employed to compensate for cognitive problems, the anxiety patients did not achieve the same performance as controls. Present study demonstrates that anxiety disorders influence processing of neutral stimuli and this influence is observable at both behavioral and electrophysiological level. The data suggests instability of neural systems responsible for information selection, working memory, engagement and focusing of attention.

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Section: Discussionmentioning

confidence: 99%

EEG source activity during processing of neutral stimuli in subjects with anxiety disorders

Gmaj¹,

Januszko²,

Kamiński³

et al. 2016

Acta Neurobiologiae Experimentalis

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show abstract

“…The visual N1 amplitude has been linked to a variety of early sensory and attentional processes as well as orienting and discrimination (for a review see Pratt, 2012). Although the of the N1 has not been studied systematically in WS, reduced amplitude of the visual N1 has been proposed to serve as an endophenotype for susceptibility to psychiatric disorders (Smit, Posthuma, Boomsa, & De Geus, 2007). The amplitude of the N2 has been shown to correlate with reduced amygdala activity to fearful expressions (Haas et al, 2009).…”

Section: Study 1 Developmental Changes In Erp Markers Of Face Procesmentioning

confidence: 99%

Genetic Mapping of Brain Plasticity Across Development in Williams Syndrome: ERP Markers of Face and Language Processing

Mills

Dai

Fishman

et al. 2013

Developmental Neuropsychology

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In Williams Syndrome (WS), a known genetic deletion results in atypical brain function with strengths in face and language processing. We examined how genetic influences on brain activity change with development. In three studies, ERPs from large samples of children, adolescents, and adults with the full genetic deletion for WS were compared to typically developing controls, and two adults with partial deletions for WS. Studies 1 and 2 identified ERP markers of brain plasticity in WS across development. Study 3 suggested that in adults with partial deletions for WS, specific genes may be differentially implicated in face and language processing.

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“…According to the literature (Hillyard et al, 1998;Di Russo et al, 2003, 2005, 2013, there are three early, sensory components which can be distinguished in the visual evoked potential that are present within two separable ROIs: the P1, and the posterior and anterior N1 (i.e., N1p and N1a). For each of these early, sensory components, ROIs were identified on the basis of known results from the scientific literature (e.g., Smit et al, 2007) and also based on the measured scalp topographies. The P1 and N1p components were analyzed in a posterior ROI including parieto-occipital electrodes (O1, O2, PO3, PO4, P7, P8, Oz) while the N1a was analyzed in an anterior ROI including frontal electrodes (Fp1, Fp2, AF3, AF4, F3, F4, Fz).…”

Section: Eeg Datamentioning

confidence: 99%

“…Finally, a peak detection algorithm was applied to the individual ERPs in order to extract peak amplitude and latency values for the components of interest. The time ranges used for identification of P1, N1a and N1p peaks were determined from a visual inspection of subjects' ERPs and through known results in the literature (e.g., Muñoz-Ruata et al, 2010;Smit et al, 2007) and were of 70-120 ms, 80-170 ms and 120-190 ms post-stimulus, respectively. All detected peaks were verified by visual inspection to confirm that each computed individual value was well-supported from the individual graphs.…”

Section: Eeg Datamentioning

confidence: 99%

Expectations induced by natural-like temporal fluctuations are independent of attention decrement: Evidence from behavior and early visual evoked potentials

Derosière¹,

Farrugia²,

Perrey³

et al. 2015

NeuroImage

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Heritability of anterior and posterior visual N1

Cited by 13 publications

References 45 publications

EEG source activity during processing of neutral stimuli in subjects with anxiety disorders

EEG source activity during processing of neutral stimuli in subjects with anxiety disorders

Genetic Mapping of Brain Plasticity Across Development in Williams Syndrome: ERP Markers of Face and Language Processing

Expectations induced by natural-like temporal fluctuations are independent of attention decrement: Evidence from behavior and early visual evoked potentials

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