Heroin-associated anthrax with minimal morbidity

Black, Heather; Chapman, Ann; Inverarity, Donald; Sinha, S.

doi:10.1136/bcr-2016-218316

Cited by 2 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anthrax is observed in the world in generally, with lower rates in developed countries. It is endemic in Africa and Asia and WHO estimates the global incidence is from 2000 to 20,000 [9,10]. Due to animal and human epidemics in a variety of regions on earth, it has a potential for use as a biological weapon and it is very difficult to monitor information related to anthrax which is still endemic in some regions.…”

Section: Introductionmentioning

confidence: 99%

A bibliometric analysis of Bacillus anthracis research published between 1975 and 2018

Savcı¹

2019

Journal of Surgery and Medicine

View full text Add to dashboard Cite

Aim: Bibliometrics is a recent field and is performed to quantitatively assess the academic quality of journals or authors using statistical procedures such as citation rates, contents, authorship relations and productivity. Although anthrax still remains important globally, the scientific literature lacks a bibliometric assessment of the anthrax literature. In this study, it is aimed to perform the bibliometric analysis of anthrax. Methods: The data in this study were extracted from the Thomson Reuters Web of Science database (Thomson Reuters, New York, NY, USA) from 1975 to December 2018. The database is accessible back to 1975 and we searched all documents using keywords [Bacillus anthracis OR anthrax] in the "Title" field. Results: WoS database search recorded a total of 5557 publications. More than half of the publications were original articles (n=3828, 68.8%). The country with the greatest number of publications was the United States of America (n=3203), followed by England (n=301) and France (n=264). The Center for Disease Control and Prevention had the most published documents about anthrax with 210 papers and 3.7% of the total literature. The most productive authors are Leppla SH, Collier RJ, and Mock M (n=236, 124, 101 documents), respectively. The most productive journal was Infection and Immunity, which covered 4.3% of the publications with 241 manuscripts. Conclusion: In this first bibliometric study in the literature about anthrax we found that nonendemic developed countries dominated the anthrax literature. This study will encourage further studies about the investigation of anthrax, which is endemic in some parts of the world.

show abstract

Section: Introductionmentioning

confidence: 99%

A bibliometric analysis of Bacillus anthracis research published between 1975 and 2018

Savcı¹

2019

Journal of Surgery and Medicine

View full text Add to dashboard Cite

show abstract

Prospect of using B. anthracis exotoxin in the design of anti-selective emergency preparations

Yanenko¹,

Zaviriukha²,

Vasylieva³

et al. 2022

Ukrainian journal of veterinary sciences

View full text Add to dashboard Cite

The relevance of the study is conditioned upon the fact that outbreaks of anthrax are periodically recorded on the territory of Ukraine, not only in ruminants, but also in pigs, fur animals, dogs, and people. The purpose of the study is to investigate the protective properties of the experimental vaccines and the abacillary vaccine “Antracol” and to prove the immunogenic effect of the extracellular toxin from the B. anthracis K-79 Z strain. Cultures of vaccine strains of anthrax were used for the experiments: B. anthracis 55, B. anthracis SB, B. anthracis K-79 Z and the “Antracol” vaccine (experimental development). Microbiological, clinical-biological, and biotechnological research methods were used in the study. The protective effect was investigated on guinea pigs (Cavia porcellus). An acute experiment was performed with a virulent strain B. anthracis 92 Z. Exotoxin was obtained from the specified cultures. The titre of the exotoxin was found in the disk precipitation reaction. The highest result regarding exotoxin production was recorded in B. anthracis K-79 Z 1 : 128 with a total protein concentration of 0.19 mg/ml, while the exotoxin of B. anthracis strain 55 with a titre of 1 : 32 showed a high total protein concentration of 0.4 mg/ml. The effect of B. anthracis exotoxins on the body was investigated by administering them to laboratory animals in different titres of exotoxins, followed by infection with the pathogenic strain B. anthracis 92 Z. The exotoxin of the vaccine strain B. anthracis K-79 Z in a titre of 1 : 64-1 : 128 shows the best protective properties against the pathogenic strain. It was found that the vaccine strains of B. anthracis SB and B. anthracis K-79 Z have the same level of protection of laboratory animals during experimental infection, which is 60%, while the vaccine from the strain B. anthracis 34F2 showed a level of protection of 20%. Based on the results of the study, it was found appropriate to use exotoxin B. anthracis in the development of prophylactic preparations against anthrax. The research results can be used by scientists and specialists in the field of veterinary medicine to develop new and improve the available vaccines for effective anthrax prevention

show abstract

Heroin-associated anthrax with minimal morbidity

Cited by 2 publications

References 8 publications

A bibliometric analysis of Bacillus anthracis research published between 1975 and 2018

A bibliometric analysis of Bacillus anthracis research published between 1975 and 2018

Prospect of using B. anthracis exotoxin in the design of anti-selective emergency preparations

Contact Info

Product

Resources

About