Herpes Simplex Virus Type 2: Bystander or Active Player in Cervical Carcinogenesis?

Abstract

Epstein-Barr virus (EBV) belongs to the group of gammaherpes viruses and is responsible for epithelial malignancies including B-cell lymphomas, lymphoproliferative disorders, nasopharyngeal, gastric and salivary gland carcinomas, breast, prostate and oral cancers. It is commonly transmitted through oral secretions. Previous studies demonstrated EBV DNA in cervicitis, precancerous (cervical intraepithelial neoplasia, CIN) and