“…Many things which are related to the decline in the our defense system, especially the cellular immune system that can trigger HZ, including aging (immunosenescence), 6,9 malnutrition, emotional stress, physical trauma, fatigue, 4 malignancies, the use of immunosuppressive drugs (such as corticosteroids, chemotherapy), 9,10 DM, transplants, HIV infection, and systemic lupus erythematosus. 6 Viruses in HZ are transmitted through direct contact with lesions in the vesicular phase to individuals who do not have immunity to this virus so it triggers the occurrence of varicella.…”