2012
DOI: 10.4103/2229-5178.93495
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Herpes zoster duplex bilateralis in an immunocompetent host

Abstract: Varicella zoster virus causes both chicken pox and herpes zoster. The phenomenon of herpes zoster occurring concurrently in two non-contiguous dermatomes involving different halves of the body is termed herpes zoster duplex bilateralis (HZDB). Few cases, reported in the literature, were seen in either an immunosuppressed host or in the older age group. Here we present a case of HZDB in an immunocompetent host, probably the first in India.

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Cited by 9 publications
(8 citation statements)
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“…In our study multidermatomal involvement was observed in 11 patients and herpeszoster duplex bilateralis and disseminated herpes zoster was observed in one case each ,all of them were immunocompromised. This is in concordance with other studies [4,10] where as Gahalaut et al has reported a case of herpeszoster duplex bilateralis in an immunocompetent individual [11]. HIV seropositivity was seen in 7% of the patients in our study and two of them had multidermatomal and one had disseminated zoster.This is similar to the study by Kar et al where they observed a seropositivity of 9.5% in 115 cases studied [12].…”
Section: Discussionsupporting
confidence: 82%
“…In our study multidermatomal involvement was observed in 11 patients and herpeszoster duplex bilateralis and disseminated herpes zoster was observed in one case each ,all of them were immunocompromised. This is in concordance with other studies [4,10] where as Gahalaut et al has reported a case of herpeszoster duplex bilateralis in an immunocompetent individual [11]. HIV seropositivity was seen in 7% of the patients in our study and two of them had multidermatomal and one had disseminated zoster.This is similar to the study by Kar et al where they observed a seropositivity of 9.5% in 115 cases studied [12].…”
Section: Discussionsupporting
confidence: 82%
“…An effective immune system maintains the viral genome in latently infected cell and prevents viral replication and spread via retrograde axonal flow to the skin. Reactivation of HZ is usually confined to a single episode and a single dermatome, though the latent viral genomes are present in many peripheral sensory ganglia [2] Factors reported to determine the occurrence of zoster include waning specific cell mediated immunity to VZV related to age, immunosuppressive disease or drug therapy, local trauma such as surgery, local therapeutic X-ray irradiation and possibly local musculoskeletal problem. Isolated case reports in the literature also document bilateral zoster.…”
Section: Discussionmentioning
confidence: 99%
“…[1] The phenomenon of herpes zoster occurring concurrently in two non-contiguous dermatomes involving different halves of the body is termed herpes zoster duplex bilateralis (HZDB). [2] …”
Section: Introductionmentioning
confidence: 99%
“…Multiple recurrences of herpes zoster has been reported in HIV and immunocompromised patients [1]. Although herpes zoster is typically unilateral, there has been only few reports of multiple dermatomal involvement [2,[7][8][9] and bilateral asymmetrical [2,9] distribution of herpes zoster lesions with incidence of approximately less than 1% [10]. This presentation has been referred to a zoster duplex unilateralis or bilateralis depending on whether one or both halves of the body is involved [1].…”
Section: Case Reportmentioning
confidence: 99%