Herpesviruses.

Varicella in Immunocompromised Children

“…Our case report suggests that immunocompromised children who experi¬ ence varicella infections may be cate¬ gorized into three clinical groups: (1) those whose disease is limited to the skin; (2) those with mild progressive illness who appear to be spared the abdominal pain, inappropriate ADH syndrome, severe encephalitis, and co¬ agulopathy; and (3) those with severe involvement who eventually demon¬ strate the full spectrum of complica¬ tions. The factors responsible for these three different clinical patterns are unknown.…”

High intrahepatic HHV-6 virus loads but neither CMV nor EBV are associated with decreased graft survival after diagnosis of graft hepatitis

“…HHV-6, CMV, EBV) usually are acquired in childhood resulting in a seroprevalence between 60% and over 90% in Central Europe [11] and the USA [12,13]. All members of the herpesviridae establish life long latency and preferentially reactivate under immunosuppression [14]. Therefore, the majority of adult transplant patients are at risk of herpesvirus reactivations.…”

Multiplex real‐time PCR for the simultaneous detection of herpes simplex virus, human herpesvirus 6, and human herpesvirus 7

“…The human herpesviruses are ubiquitous within human populations; they remain latent within the body after primary infection and often become reactivated in immunocompromised individuals (1, 2). Both primary and recurrent herpesvirus infections may lead to CNS infection and disease.…”