Hesperidin attenuate fibrillation and cytotoxicity of human insulin: Role of secondary structure and its hydrophobicity in protein aggregation

Amyloid detection in neurodegenerative diseases using MOFs

“…23 Insulin-derived amyloidosis, for example, occurs when insulin aggregates into amyloid fibrils at injection sites, disrupting glycemic control and potentially causing tissue necrosis. 24 Medullary thyroid cancer (MTC) associated with calcitonin has diagnostic challenges due to low incidence and testing costs, resolved potentially by detecting procalcitonin levels. 25…”