Hesperidine, a flavonoid antioxidant decrease oxidative stress and prevent fœtal molformations in experimental diabetic pregnancy

Ouali, Kheireddine; Trea, Fouzia; Toumi, L.; Bairi, Abdelmadjid; Maurel, Daniel; Guellati, M.

doi:10.1007/s10298-007-0253-3

Cited by 3 publications

(1 citation statement)

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“…The smell of this vegetable and its medicinal properties may be also linked to the presence of coumarins. The antioxidant property of tannins, flavonoids and coumarins make them capable of protection against free radicals which are responsible of more than 200 human diseases including cardiovascular disease, cancer, arthritis, sight disorder and ageing (Oszmianski et al, 2007;Ouali et al, 2007;Mir et al, 2012;Adjatin et al, 2013). Steroids are known for their analgesic, antimicrobial, anti-inflammatory and cardiotonic properties (Hossain et al, 2013;Ekissi et al, 2014).…”

Section: Phytochemical Screeningmentioning

confidence: 99%

Phytochemical Screening and Toxicity of Lippia multiflora Moldenke, a Minor Aromatic Leafy Vegetable Consumed in Benin

Djengue¹,

Dansi²,

Assogba³

et al. 2017

Int. J. Curr. Res. Biosci. Plant Biol.

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A b s t r a c t A r t i c l e I n f oLippia multiflora Moldenke, is a minor aromatic leafy vegetable mainly consumed in central Benin that belong to the country's neglected and underutilised species (NUS). Extracts of its leaves and flowers collected from six different zones (Bantè, Dassa-Zoumè, Djidja, Glazoué, Savalou and Savè) were assessed for phytochemical composition and tested for cytotoxicity using brine shrimp lethality bioassay. The phytochemical screening revealed the presence of almost the same phytochemical groups (cathetic and gallic tannins, flavonoids, anthocyanins, leucoanthocyanes, triterpenoids, mucilage, coumarins and the reducing compounds) in both leaves and flowers from all sites with variable abundances. Alkaloids were found only in leaves while steroids, quinone derivatives and combined anthracene C-heterosides were identified uniquely in flowers. The nature and the functions of the compounds found justify the perceived medicinal values of the species. Extracts from both leaves and flowers showed positive action on shrimp larvae but with CL 50 of (13.28±1.52 mg/ml for leaves; 0.46±0.05 mg/ml for flowers) superior to 0.1mg/ml, hence indicating the non-toxicity of Lippia multiflora.

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Section: Phytochemical Screeningmentioning

confidence: 99%