The existence of infinitely many homoclinic solutions for the fourth-order differential equation φ p u ″ t ″ + w φ p u ′ t ′ + V ( t ) φ p u t = a ( t ) f ( t , u ( t ) ) , t ∈ R is studied in the paper. Here φ p ( t ) = t p − 2 t , p ≥ 2 , w is a constant, V and a are positive functions, f satisfies some extended growth conditions. Homoclinic solutions u are such that u ( t ) → 0 , | t | → ∞ , u ≠ 0 , known in physical models as ground states or pulses. The variational approach is applied based on multiple critical point theorem due to Liu and Wang.