Heterogeneity in Depression Symptoms and Health Status Among Older Adults

Mora, Pablo A.; Beamon, Teerah; Preuitt, LeAnn; DiBonaventura, Marco; Leventhal, Elaine A.; Leventhal, Howard

doi:10.1177/0898264312440323

Cited by 12 publications

(16 citation statements)

References 32 publications

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“…It has been found that presentation of depressive symptoms is heterogeneous also among older adults (Chen, Eaton, Gallo, & Nestadt, 2000;Mora et al, 2012). This means that two persons with the same score on a depression scale will not necessarily have similar symptoms.…”

Section: Introductionmentioning

confidence: 94%

Life-space mobility and dimensions of depressive symptoms among community-dwelling older adults

Polku

Mikkola

Portegijs

et al. 2014

Aging & Mental Health

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Section: Introductionmentioning

confidence: 94%

Life-space mobility and dimensions of depressive symptoms among community-dwelling older adults

Polku

Mikkola

Portegijs

et al. 2014

Aging & Mental Health

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“…The heterogeneity of depression in late life is supported by recent studies of community-dwelling older adults that identified distinct latent-class subtypes of depression (Lee, Leoutsakos, Lyketsos, Steffens, Breitner, & Norton, 2012; Mora et al, 2012). Lee et al (2012) identified three subgroups of depressed older adults: those with high levels of virtually all depressive symptoms (62%), those with some elevated symptoms but a low probability of endorsing all depressive symptoms (21%), and a subgroup with primarily somatic symptoms such as psychomotor changes, sleep disturbances, and fatigue (17%).…”

Section: Resultsmentioning

confidence: 94%

“…Lee et al (2012) identified three subgroups of depressed older adults: those with high levels of virtually all depressive symptoms (62%), those with some elevated symptoms but a low probability of endorsing all depressive symptoms (21%), and a subgroup with primarily somatic symptoms such as psychomotor changes, sleep disturbances, and fatigue (17%). In another study of community-dwelling older adults ( N = 420), four distinct patterns of depression symptoms emerged: low depression symptoms (68%), high depression symptoms (5%), subthreshold depression with anhedonia but few somatic complaints and low levels of negative affect and negative interpersonal feelings (18%), and subthreshold depression with somatic complaints, anhedonia and negative interpersonal feelings (9%; Mora et al, 2012). Given the heterogeneity of depressive symptoms, the authors also underscored the need for clinicians to consider diverse presentations when assessing depression in older adults (Lee et al, 2012; Mora et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

“…In another study of community-dwelling older adults ( N = 420), four distinct patterns of depression symptoms emerged: low depression symptoms (68%), high depression symptoms (5%), subthreshold depression with anhedonia but few somatic complaints and low levels of negative affect and negative interpersonal feelings (18%), and subthreshold depression with somatic complaints, anhedonia and negative interpersonal feelings (9%; Mora et al, 2012). Given the heterogeneity of depressive symptoms, the authors also underscored the need for clinicians to consider diverse presentations when assessing depression in older adults (Lee et al, 2012; Mora et al, 2012). …”

Section: Resultsmentioning

confidence: 99%

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Towards a new conceptualization of depression in older adult cancer patients: a review of the literature

Saracino

Rosenfeld

Nelson

2015

Aging & Mental Health

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Objectives Identifying depression in older adults with cancer presents a set of unique challenges, as it combines the confounding influences of cancer and its treatment with the developmental changes associated with aging. This paper reviews the phenomenology of depression in older adults, and individuals diagnosed with cancer. Method PsychInfo, PubMed, Web of Science, and Google Scholar databases were searched for English-language studies addressing the phenomenology, symptoms, or assessment of depression in older adults and those with cancer. Results The Diagnostic and Statistical Manual for Mental Disorders (DSM) criteria that appear to be relevant to both older adults and cancer patients are anhedonia, concentration difficulties, sleep disturbances, psychomotor retardation/agitation, and loss of energy. Possible alternative criteria that may be important considerations included constructs such as loss of purpose, loneliness, and irritability in older adults. Among cancer patients, tearfulness, social withdrawal, and not participating in treatment despite ability to do so were identified as potentially important symptoms. Conclusions Current DSM criteria may not adequately assess depression in older cancer patients and alternative criteria may be important to inform the understanding and identification of depression in this population. Enhancing diagnostic accuracy of depression is important as both the over-diagnosis and under-diagnosis is accompanied with significant costs. Thus, continued research exploring the phenomenology and identifying effective indicators of depression in older cancer patients is needed.

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“…Previous LPA studies using the Center for Epidemiologic Studies Depression Scale (CES-D) (Radloff, 1977) each identified at least three unique latent classes based on depressive symptomatology (Hybels et al, 2011; Hybels et al, 2013; Mora et al, 2012) among elderly populations; but, none focused on a community sample of female residents of a geographic area vulnerable to disaster. The Women and Their Children’s Health (WaTCH) Study was designed to assess the effects of the DHOS on the physical and mental health of southeastern Louisiana women and children.…”

Section: Introductionmentioning

confidence: 99%

Exploring heterogeneity and correlates of depressive symptoms in the Women and Their Children's Health (WaTCH) Study

Gaston

Nugent

Peters

et al. 2016

Journal of Affective Disorders

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Introduction Oil spill exposures are associated with increased levels of depression, which is often measured using continuous scores or dichotomous cut points on screening tools in population-based studies. Latent profile analysis can overcome analytic limitations such as 1) masking of heterogeneity in outcomes among people within dichotomous categories and 2) loss of information about symptom patterns among those with the same continuous score. This study examined variation in depressive symptoms and assessed the associations between depressive symptomatology and oil spill exposure, socioeconomic risk factors, and social capital. Methods Between 2012 and 2014, we interviewed 2852 women in southeastern Louisiana. We performed latent profile analysis then tested the adjusted associations between sociodemographic characteristics, oil spill exposure and latent class membership. Results Results indicated a three-class solution in which classes varied by symptom severity as the best fit. The strongest associations were among women with the most severe depressive symptoms, who were less educated, were more economically vulnerable, and had the least social support compared to women with no depressive symptoms. Limitations This study is limited by its cross-sectional design and the self-reported nature of exposures and depressive symptoms, but results are consistent with prior literature. Conclusions Our results support the conventional use of screening tools to estimate depressive symptomatology. Nevertheless, the identification of subgroups within study participants highlights an important finding: the subgroups were comprised of characteristically different women with varying levels of depressive symptoms, a discovery that would have been overlooked if the CES-D was used conventionally.

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Heterogeneity in Depression Symptoms and Health Status Among Older Adults

Cited by 12 publications

References 32 publications

Life-space mobility and dimensions of depressive symptoms among community-dwelling older adults

Life-space mobility and dimensions of depressive symptoms among community-dwelling older adults

Towards a new conceptualization of depression in older adult cancer patients: a review of the literature

Exploring heterogeneity and correlates of depressive symptoms in the Women and Their Children's Health (WaTCH) Study

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