Heterogeneity of tumor biophysical properties and their potential role as prognostic markers
Anja Madleine Markl,
Daniel Nieder,
Diana Isabel Sandoval-Bojorquez
et al.
Abstract:Progress in our knowledge of tumor regulatory mechanisms and complexity led to the understanding of the physical parameters of cancer cells and their microenvironment, including the mechanical, thermal, and electrical properties, solid stress, and liquid pressure, as critical regulators of tumor progression and potential prognostic markers associated with clinical outcomes. The biological hallmarks of cancer and physical abnormalities of tumors are mutually reinforced, promoting a vicious cycle of tumor progre… Show more
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