Heterogeneous Henry reaction of aldehydes: Diastereoselective synthesis of nitroalcohol derivatives over Mg-Al hydrotalcites

MgAl-Layered Double Hydroxide Solid Base Catalysts for Henry Reaction: A Green Protocol

“…To the author's knowledge, this is the second trial after pioneering work by V. J. Bulbule et al [21]. However, the present study should be the first extensive study to understand the effect of mesoporous and basic nature of such catalysts in Henry reaction under the reaction conditions.…”

“…The catalytic reaction using different investigated catalysts were carried out between 1a and 2a under conventional and microwave irradiation and the obtained results are given in Table 2 It is seen from Fig.4 that MgAl-HT-RH displays an effectual activity and higher % yield in comparison to the literature data [21]. The higher activity of this catalyst is due to the high surface area (134 m …”

Magnetically Separable Base Catalysts: Heterogeneous Catalysis vs. Quasi-Homogeneous Catalysis

“…Usually, these condensations are catalyzed under homogeneous conditions by bases such as primary, secondary and tertiary amines. During the last decades, different solid base catalysts have been utilized to perform the Knoevenagel and nitroaldol condensations [38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54]. In addition, recent investigations show that magnetic nanoparticles functionalized with amine groups are effective catalysts in Knoevenagel condensation [55][56][57].…”

Synthetic hydrotalcites from different routes and their application as catalysts and gas adsorbents: a review

“…In the reaction of benzaldehyde and chlorobenzene with nitromethane, CsNaX catalyst was known to produce nitroalkenes at 80% yield at 413 K. [187] In another study, Mg-Al mixed oxides prepared by calcination of hydrotalcite were used to catalyze the nitroaldol condensation to nitroalcohols at 95% yield. [188] …”