Heterotaxy polysplenia syndrome in an adult female with complete endocardial cushion defect

Esmat, Habib Ahmad; Naseri, Mohammad Wali; Shirzai, Asadullah

doi:10.1016/j.radcr.2021.02.015

Cited by 1 publication

(1 citation statement)

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“…Although the patient had only one identifiable risk factor for thromboembolism, the use of oral contraceptive pills and the presence of vena cava malformation likely contributed to the extensive bilateral DVT. Moreover, our patient did not have the classic association of heterotaxy polysplenia syndrome, which is a rare group of congenital abnormal arrangements of the abdominal and thoracic organs that are associated with the presence of two or more spleens [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Extensive Deep Vein Thrombosis With Intraabdominal Extension Triggered by Oral Contraceptive Use in a Young Patient With Interrupted Inferior Vena Cava With Azygos Continuation: A Case Report

Abu Sabha,

Bairmani,

Alfroukh

et al. 2023

Cureus

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Congenital malformations of the inferior vena cava (IVC) are rare and often asymptomatic, typically discovered incidentally during imaging. However, these anomalies can result in circulatory stasis, impede venous return, and serve as predisposing factors for thrombus formation. Here, we present a unique case of a 28-year-old female patient who was found to have interrupted IVC with azygos continuation, an exceedingly rare IVC anomaly, during a work-up of extensive bilateral deep vein thrombosis (DVT) with an intraabdominal extension which was triggered by recent combined oral contraceptive pills (OCP) use. This case highlights the importance of considering vena cava malformations as an underlying cause for extensive DVT, even in the absence of conventional risk factors. Clinicians should be aware of the potential association between congenital vena cava anomalies and thrombotic events, as early recognition and appropriate management are crucial for preventing complications such as pulmonary embolism.

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Section: Discussionmentioning

confidence: 99%