Heterotopic neuroglial tissue as a congenital laterocervical mass: A case report

Tambay, M. Castrillo; Rodríguez, I. Zubillaga; Gil, Yolanda Rodríguez; García, Alfredo; Saez, R.S.; Moreno, Juan

doi:10.1016/j.ijom.2007.05.025

Cited by 3 publications

(6 citation statements)

References 8 publications

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“…Heterotopic glial tissue is an extremely rare clinical entity presenting in head and neck region secondary to abnormal development of mature central nervous system tissue at an abnormal location with a likely limited growth potential. 4,5 It has been reported to occur in nasopharynx, internal auditory canal, intraoral mass, hard palate, and mastoid bone. 4,5 Few cases has also been reported in orbit presenting as proptosis and strabismus.…”

Section: Discussionmentioning

confidence: 99%

“…4,5 It has been reported to occur in nasopharynx, internal auditory canal, intraoral mass, hard palate, and mastoid bone. 4,5 Few cases has also been reported in orbit presenting as proptosis and strabismus. [6][7][8][9] The underlying cause for heterotopic or ectopic glial tissue has been theorized to be related to the abnormality in development of facial and skull bone plates but can also be seen isolated in the form of nodules without any connection to the central nervous system.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] Histopathological evaluation usually reveals fibrous and vascularized connective tissues with scattered mature glial tissue in a fibrillary background. [4][5][6][7][8][9][10] The cells are predominantly astrocytes with sparse or absent neurons, and this differentiates it with an encephalocele where abundant neurons will be noted. As the age of the patient increases, the fibrous component of glial heterotopic masses increases significantly with minimal glial tissues.…”

Section: Discussionmentioning

confidence: 99%

“…There should be efforts to look for presence of any ependymal cells, meninges, and choroidal plexus since the presence of these helps in differential diagnosis of other conditions like meningoencephaoloceles. 4 Treatment recommended for glial heterotopia is a complete excision of the mass even though there is no malignant or metastatic potential. [4][5][6][7][8][9] There is a controversy in the literature regarding the growth potential of these masses, but many believe that conservative management risks a possible continued growth with its attendant complications depending on the site.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Glial Heterotopia or Ectopic Brain Masquerading as a Dacyrocystocele

Ali¹,

Kamal²,

Vemuganti

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Glial heterotopia is an extremely rare clinical entity mostly presenting in head and neck region secondary to an abnormal development of an isolated mature central nervous system (CNS) tissue at an abnormal location without any continuity with the brain, spinal cord, or meninges. Its origin is either due to mechanical isolation of glial tissues by the developing cranial bones or secondary to misdirected or sequestered embryonic neuroectodermal stem cells outside the CNS. The authors present an exceptionally rare case of a heterotopic glial nodule masquerading as a dacryocystocele, its radiological features along with a brief clinicopathological correlation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Glial Heterotopia or Ectopic Brain Masquerading as a Dacyrocystocele

Ali¹,

Kamal²,

Vemuganti

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

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“…On the other hand, patients with extracranial masses commonly present with respiratory distress and feeding difficulty [10]. Some developmental anomalies have been associated with NH; these include cleft palates, Pierre Robin syndrome, congenital heart disease, pectus excavatum and micrognathia [11,12].…”

Section: Discussionmentioning

confidence: 99%

Intracranial extracerebral neuroglial heterotopia with parapharyngeal extension: pre-natal and post-natal imaging findings

Ferraz-Filho

Torres²,

Vaz-Oliani³

et al. 2012

BJR

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ABSTRACT. We report an unusual case of intracranial extracerebral neuroglial heterotopia (IENH) presenting with parapharyngeal extension. Neuroglial heterotopias are rarely reported pre-natally and, to our knowledge, there are no reported cases presenting pre-natal imaging findings of IENH with parapharyngeal extension. Because pre-and post-natal imaging studies are essential to diagnose IENH and plan surgical treatment, radiologists should be familiar with this rare condition. Neuroglial heterotopias (NHs) are rare congenital lesions characterised by the presence of differentiated neuroectodermal tissue in locations where neuronal and glial cells do not typically occur [1]. These lesions usually involve the head and neck regions and are more commonly described in extracranial locations such as the nose and nasopharynx, oral cavity, oropharynx, palate, tongue, lips, scalp and orbit. Although intracranial extracerebral NH has been described more frequently with the increased availability of MRI, it remains a very rare condition [2].Intracranial extracerebral neuroglial heterotopias (IENHs) with parapharyngeal or oropharyngeal extension have been presented in a limited number of reports [2,3]. To our knowledge, pre-natal imaging findings of this uncommon combination have not been reported before. We report a case of IENH with parapharyngeal extension and describe its antenatal and post-natal imaging features. Case reportA 28-year-old pregnant female (gravida 3, para 2) was referred to our institution after an obstetric ultrasound examination at 25 weeks' gestation identified a foetal intracranial mass with extension to the left side of the neck. A repeat obstetric ultrasound performed in our department showed an osseous malformation in the left frontotemporal area of the cephalic pole resulting from a solid, round, predominantly hypoechoic intracranial mass (4.864.2 cm) with an anechoic area inside. This mass appeared to be contiguous with a predominantly cystic mass (6.765.9 cm) on the left side of the neck (Figure 1). A foetal MRI was performed at 27 weeks gestation; this showed a solid cystic mass lesion in the left anterolateral portion of the craniofacial region (Figure 2). Subsequent ultrasound evaluations showed that the mass had remained stable during pregnancy.The female infant was delivered pre-term by the ex utero intrapartum treatment procedure (EXIT) at 36 weeks gestation because of the risk of airway compression. Apgar scores at 1 min and 5 min were 9 and 10, respectively. The patient, who weighed 3045 g at birth, was admitted into the neonatal intensive care unit on mechanical ventilation. On clinical examination, the neonate had a large, soft, compressible cervical mass involving the frontotemporal region of the head.An MRI scan performed at the age of 1 day showed a large heterogeneous lesion with solid and cystic components. The solid component was an intracranial extracerebral lesion located in the left middle cranial fossa that presented a signal intensity similar to that of cerebral parenchyma...

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An Oropharyngeal Obstructive Lesion in a Neonate

et al. 2021

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Neonatal HNT in the pharynx is a rare cause of respiratory distress and poor feeding in the newborn, but must be differentiated from teratoma, encephalocele, and nasal glioma. While surgical resection is the preferred treatment modality, we posit there is a role for sclerosis of the glial heterotopic cyst if complete surgical excision is not possible or carries risk of high morbidity. Here, we present a case of a 7-day-old neonate presenting with acute respiratory distress found to have a nasopharyngeal/oropharyngeal mass ultimately treated with sclerotherapy at 9 months of age.

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Heterotopic neuroglial tissue as a congenital laterocervical mass: A case report

Cited by 3 publications

References 8 publications

Glial Heterotopia or Ectopic Brain Masquerading as a Dacyrocystocele

Glial Heterotopia or Ectopic Brain Masquerading as a Dacyrocystocele

Intracranial extracerebral neuroglial heterotopia with parapharyngeal extension: pre-natal and post-natal imaging findings

An Oropharyngeal Obstructive Lesion in a Neonate

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