Heterotopic ossification in the post cruciate ligament of the knee: a case report and literature review

Background: Heterotopic ossification (HO) is the formation of bone in soft tissue resultant from inflammatory processes. Lesion formation after arthroscopic procedures is an uncommon but challenging complication. Optimal prophylaxis and management strategies have not been clearly defined. Purpose: To present a scoping review of the pathophysiology, risk factors, diagnostic modalities, prophylaxis recommendations, and current treatment practices concerning HO after arthroscopic management of orthopaedic injuries. Study Design: Scoping review; Level of evidence, 4. Methods: A scoping review via a PubMed search was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. The search strategy was based on the terms “heterotopic ossification” AND “arthroscopy.” The clinical outcomes review included studies on the arthroscopic management of orthopaedic injuries in which the primary subject matter or a secondary outcome was the development of HO. An analysis of the pathophysiology, diagnostic modalities, and management options was reported. Results: A total of 43 studies (33,065 patients) reported on HO after hip arthroscopy, while 21 (83 patients) collectively reported on HO after arthroscopic procedures to the shoulder, elbow, knee, or ankle; however, management techniques were not standardized. Identified risk factors for HO included male sex and mixed impingement pathology, while intraoperative capsular management was not suggested as a contributing factor. Diagnosis of ossification foci was performed using radiography and computed tomography. The rate of HO after hip arthroscopy procedures approached 46% without prophylaxis, and administration of nonsteroidal anti-inflammatory drugs (NSAIDs) decreased occurrence rates to 4% but carries associated risks. External beam radiation has not been exclusively studied for use after arthroscopic procedures. Conclusion: HO is a known complication after arthroscopic management of orthopaedic injuries. NSAID prophylaxis has been demonstrated to be effective after hip arthroscopy procedures. Patients with persistent symptoms and mature lesions may be indicated for surgical excision, although variability is present in patient-reported outcome scores postoperatively.

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“… # References 1, 2, 10 -13, 20, 22, 24 -26, 28, 32, 35, 36, 38, 39, 41, 44, 46, 49, 51, 52, 58, 71, 74, 76, 80, 82, 85, 89 …”

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confidence: 99%

Heterotopic Ossification After Arthroscopic Procedures: A Scoping Review of the Literature

Zhou

Gee

Hansen

et al. 2022

Orthopaedic Journal of Sports Medicine

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“…Few cases of noninstrumented native knee intra-articular HO have been reported. The most common presentation involves ossification within the substance of a cruciate or collateral ligament, with or without precipitating trauma [ 14 – 19 ]. However, intra-articular knee HO after a tibial IM nail may be more common than previously believed.…”

Section: Discussionmentioning

confidence: 99%

Excision of Intra‐articular Knee Heterotopic Ossification Using a 70° Arthroscope

Hoffer,

Lin,

Kalani

et al. 2024

Case Reports in Orthopedics

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Heterotopic ossification is ectopic lamellar bone formation within soft tissue and can result in significant functional limitations. There are multiple underlying etiologies of HO including musculoskeletal trauma and traumatic brain injury. Intra‐articular HO of the knee is rare and is typically located within the cruciate ligaments. We report a case of a 24‐year‐old female who presented with worsening right knee pain and limited knee extension two and a half years after a motor vehicle crash with multiple lower extremity fractures. Physical examination of the knee revealed anterior pain, limited extension, and a palpable infrapatellar prominence. Imaging showed a retropatellar tendon, intra‐articular excrescence of bone proximal to the anterior tibial plateau. Diagnostic arthroscopy with a 70° arthroscope identified HO at the proximal anterior tibial plateau, which was excised with a high‐speed burr under direct visualization. At the three‐month follow‐up, the patient remained asymptomatic and returned to sport. Retropatellar tendon, intra‐articular anterior knee HO is a rare but debilitating clinical entity that can be successfully and safely managed with excision under direct visualization using a 70° arthroscope.

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“…Nevertheless, most clinical studies did not report such complications [ 9 ]. Heterotopic ossification (HO) is defined as the formation of bone within extra-skeletal structures [ 10 ]. As far as we know, no cases have been reported in the literature about HO post-sMCL pie-crusting.…”

Section: Introductionmentioning

confidence: 99%

Heterotopic ossification postsuperficial medial collateral ligament pie-crusting: a case report

Aldhilan,

Alshahrani,

Almogbil

2024

Journal of Surgical Case Reports

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Anterior cruciate ligament and meniscus tears are common among sports injuries. There are different techniques for addressing anterior cruciate ligament and meniscus tears, with distinct indications, advantages, and disadvantages. We present the case of a 23-year-old male who underwent right anterior cruciate ligament reconstruction and posterior horn medial meniscus repair using an all-inside technique via superficial medial collateral ligament (sMCL) pie-crusting. Clinical examination and radiological investigations a few months later identified calcifications on the medial side of the right knee. We diagnosed the patient with heterotopic ossification post-sMCL pie-crusting; no apparent causal factors were present. To our knowledge, there have been no documented instances of heterotopic ossification following sMCL pie-crusting. In conclusion, heterotopic ossification may occur after sMCL pie-crusting; further studies are needed on this subject.

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Heterotopic ossification in the post cruciate ligament of the knee: a case report and literature review

Cited by 9 publications

References 18 publications

Heterotopic Ossification After Arthroscopic Procedures: A Scoping Review of the Literature

Heterotopic Ossification After Arthroscopic Procedures: A Scoping Review of the Literature

Excision of Intra‐articular Knee Heterotopic Ossification Using a 70° Arthroscope

Heterotopic ossification postsuperficial medial collateral ligament pie-crusting: a case report

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