Heterotopic Pancreas Located in the Ileum

Abstract

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Severe obscure gastrointestinal bleeding from Meckel’s diverticulum with predominant ectopic pancreatic tissue

“… 5 Autopsy studies have revealed that the heterotopic pancreas (HP) affects a low percentage of the population, ranging from 0.5% to 14.0%. 13 This clinical condition mostly affects the stomach, duodenum and jejunum, but it can also occur in any site of the digestive system, including the oesophagus, terminal ileum, omentum, mesentery, spleen, liver, MD, colon, gallbladder, urinary bladder, lung and lymph nodes. 13 Compared to the ileum, the proximal small intestine, duodenum and stomach are more likely to have heterotopic pancreatic tissues that occurs alone.…”

Successful preoperative diagnosis of heterotopic pancreas in the duodenum

“…According to literature, HP is a rare occurrence found in 0.5–14% of all autopsies performed and 0.5% of all upper abdominal laparotomies [3,4]. The first reported case in history was documented in 1729 by Schultz, but the first histological confirmation was not until 1859 by Klob [4,5].…”

“…HP has a predilection for the stomach (25–30%), duodenum (15–30%) and jejunum (15–20%), but can be found anywhere along the gastrointestinal tract. Extra-intestinal occurrences of HP include the liver, biliary tract, ampulla of Vater, gallbladder, Meckel’s diverticulum, umbilicus, fallopian tubes, pelvis, mesocolon, small bowel mesentery, spleen, lungs and mediastinum, albeit very rarely [[3], [4], [5], [6]]. When involving the gastrointestinal tract, it is most frequently located in the submucosal layer [5].…”

An Unusual Lung Mass of Heterotopic Pancreatic Tissue in a Neonate With an Elevated Immunoreactive Trypsinogen on Newborn Screen

“…HP has a predilection for the stomach (25%–38%), duodenum (17%–36%), and jejunum (15%–22%) but can be found anywhere along the gastrointestinal tract. Extraintestinal HP has been found in the liver, biliary tract, gallbladder, umbilicus, and spleen, 1 with reports of HP in the lungs being exceedingly rare. Our patient is a neonate with TEF-EA who was found to have a bronchopulmonary foregut malformation (BPFM) containing heterotopic pancreatic tissue with the presence of acini, ducts, and islet cells similar in appearance to a normal pancreas.…”