Heterozygous COL5A1 deletion in a cat with classical Ehlers–Danlos syndrome

Abstract

Clinical and histopathological phenotype of the affected cat. (a) Hyperextensible skin. (b) Histopathology of a skin biopsy showed reduced dermal thickness and irregularly arranged collagen fibers in the affected cat. (c) Skin of an unaffected control cat. Hematoxylin and eosin staining, scale bars = 200 μm.