1994
DOI: 10.1016/0195-6701(94)90065-5
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Hexachlorophane powder and neonatal staphylococcal infection

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Cited by 17 publications
(12 citation statements)
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“…It has been shown previously that hexachlorophane powder is effective as part of an umbilical care regimen, and indeed that its discontinuation can lead to outbreaks of S. aureus infection. 4,5 Hexachlorophane powder was partially successful in the control of the S. aureus PT53,85 outbreak we described previously, 1 however its maximal effectiveness is only likely to be achieved when used with other infection control measures. Indeed, we subsequently had to instigate further control measures, including topical mupirocin, for babies colonized or infected with S. aureus, before our outbreak was successfully contained.…”
Section: Discussionmentioning
confidence: 81%
“…It has been shown previously that hexachlorophane powder is effective as part of an umbilical care regimen, and indeed that its discontinuation can lead to outbreaks of S. aureus infection. 4,5 Hexachlorophane powder was partially successful in the control of the S. aureus PT53,85 outbreak we described previously, 1 however its maximal effectiveness is only likely to be achieved when used with other infection control measures. Indeed, we subsequently had to instigate further control measures, including topical mupirocin, for babies colonized or infected with S. aureus, before our outbreak was successfully contained.…”
Section: Discussionmentioning
confidence: 81%
“…456,457 However, in many cases, when antiseptic treatments have been discontinued, increased rates of cord colonization and infection have been found. 458,459 In general, wide variation in trial design, small sample sizes with insufficient power to assess impact on infections, and inconsistent comparisons between different regimens have contributed to the largely conflicting literature on the impact of cord-care regimens.…”
Section: Umbilical Cord Antisepsismentioning
confidence: 99%
“…However, several studies have shown that this practice has led to a significant increase in staphylococcal umbilical colonisation, which in turn may lead to an increase in neonatal infections, including SSSS and methicillin resistant S aureus outbreaks. [49][50][51] Finally, the recent pressure to discharge patients early from hospitals, particularly mothers and their newborn babies, may serve to dissipate outbreaks (including SSSS)-caused by hospital staV in close contact with neonates-into the community. 6 While individual cases can easily be treated by the primary health care team, delays in recognising an outbreak mean that carriers still working in the hospital will continue to infect more patients until identified, isolated, and treated.…”
Section: Discussionmentioning
confidence: 99%