Hexapoda: Comparative Aspects of Later Embryogenesis and Metamorphosis

Jockusch, Elizabeth L.; Smith, F. W.

doi:10.1007/978-3-7091-1868-9_3

Cited by 20 publications

(26 citation statements)

References 475 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, many GO terms related to leg formation and proximodistal pattern formation were highly enriched in the genes in cluster 9 (“proximaldistal pattern formation” with p = 4.48e-05), cluster 10 (“leg disc development” with p = 7.85e-20) and cluster 12 (“leg disc development” with p = 4.32e-12) ( S1 Table ). Since antennae and maxillary palps are serially homologue to thoracic appendages, pathways involved in leg, antenna and maxillary palp development are likely to share key regulators [ 17 , 65 , 75 – 80 ], suggesting that genes found in these clusters may also play a role in antenna or maxillary palp development.…”

Section: Resultsmentioning

confidence: 99%

Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

Torres-Oliva¹,

Schneider²,

Wiegleb³

et al. 2018

PLoS Genet

View full text Add to dashboard Cite

Drosophila melanogaster head development represents a valuable process to study the developmental control of various organs, such as the antennae, the dorsal ocelli and the compound eyes from a common precursor, the eye-antennal imaginal disc. While the gene regulatory network underlying compound eye development has been extensively studied, the key transcription factors regulating the formation of other head structures from the same imaginal disc are largely unknown. We obtained the developmental transcriptome of the eye-antennal discs covering late patterning processes at the late 2nd larval instar stage to the onset and progression of differentiation at the end of larval development. We revealed the expression profiles of all genes expressed during eye-antennal disc development and we determined temporally co-expressed genes by hierarchical clustering. Since co-expressed genes may be regulated by common transcriptional regulators, we combined our transcriptome dataset with publicly available ChIP-seq data to identify central transcription factors that co-regulate genes during head development. Besides the identification of already known and well-described transcription factors, we show that the transcription factor Hunchback (Hb) regulates a significant number of genes that are expressed during late differentiation stages. We confirm that hb is expressed in two polyploid subperineurial glia cells (carpet cells) and a thorough functional analysis shows that loss of Hb function results in a loss of carpet cells in the eye-antennal disc. Additionally, we provide for the first time functional data indicating that carpet cells are an integral part of the blood-brain barrier. Eventually, we combined our expression data with a de novo Hb motif search to reveal stage specific putative target genes of which we find a significant number indeed expressed in carpet cells.

show abstract

Section: Resultsmentioning

confidence: 99%

Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

Torres-Oliva¹,

Schneider²,

Wiegleb³

et al. 2018

PLoS Genet

View full text Add to dashboard Cite

show abstract

“…Reiterative translation symmetry of segmentation controlled by the "segmentation clock" based on a mechanism characterized by oscillating gene expression was also found in insects [56,93,96,97]. In Drosophila and other hexapods, activation and repression of Hox genes by gap genes, which are part of the segmentation cascade, set up regionalized expression of the Hox genes [98]. It is possible that pair rule gene orthologs are part of an ancestral segmentation clock mechanism [56].…”

Section: Metamerism In Bilateria: Wnt and Notch Signaling Pathwaysmentioning

confidence: 91%

Symmetry Transformations in Metazoan Evolution and Development

Isaeva

Kasyanov

2021

Symmetry

View full text Add to dashboard Cite

In this review, we consider transformations of axial symmetry in metazoan evolution and development, the genetic basis, and phenotypic expressions of different axial body plans. In addition to the main symmetry types in metazoan body plans, such as rotation (radial symmetry), reflection (mirror and glide reflection symmetry), and translation (metamerism), many biological objects show scale (fractal) symmetry as well as some symmetry-type combinations. Some genetic mechanisms of axial pattern establishment, creating a coordinate system of a metazoan body plan, bilaterian segmentation, and left–right symmetry/asymmetry, are analysed. Data on the crucial contribution of coupled functions of the Wnt, BMP, Notch, and Hedgehog signaling pathways (all pathways are designated according to the abbreviated or full names of genes or their protein products; for details, see below) and the axial Hox-code in the formation and maintenance of metazoan body plans are necessary for an understanding of the evolutionary diversification and phenotypic expression of various types of axial symmetry. The lost body plans of some extinct Ediacaran and early Cambrian metazoans are also considered in comparison with axial body plans and posterior growth in living animals.

show abstract

“…Data from Oncopeltus has been used as a reference point for comparison with noninsect arthropods in a broader evolutionary context (Prpic, Janssen, Wigand, Klingler, & Damen, 2003;Schaeper, Wimmer, & Prpic, 2013). Appendage patterning seems to be a very highly conserved process in insects, thus the utility of Oncopeltus in this field is not notably higher than other species (with larval limbs), except as an additional data point to confirm conservation (Angelini & Kaufman, 2005b;Jockusch & Smith, 2015).…”

Section: Appendage Patterningmentioning

confidence: 99%

Oncopeltus fasciatus as an evo‐devo research organism

Chipman

2017

Genesis

View full text Add to dashboard Cite

The large milkweed bug Oncopeltus fasciatus was one of the main study insects for a range of biological questions throughout much of the 20 century. Its importance waned with the introduction of Drosophila melanogaster as a genetic model organism. The evo-devo revolution of the turn of the century re-introduced Oncopeltus into the scientific community, and it has proved increasingly useful, mostly within a comparative context for evolution driven research. The last few years have seen a number of significant contributions to our understanding of the evolution of developmental processes in insects, and in arthropods in general, arise from work on Oncopeltus. This review presents some of the key studies and shows how they have provided new insights into evolutionary questions. The advent of whole genome sequencing and genome editing techniques is reducing the gap between Drosophila and (re-)emerging systems such as Oncopeltus. We expect that the ease of work on Oncopeltus and its pivotal phylogenetic position will contribute to the expansion of its use within the evo-devo community and more broadly in arthropod research.

show abstract

Hexapoda: Comparative Aspects of Later Embryogenesis and Metamorphosis

Cited by 20 publications

References 475 publications

Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

Symmetry Transformations in Metazoan Evolution and Development

Oncopeltus fasciatus as an evo‐devo research organism

Contact Info

Product

Resources

About