Actuators play an important role in modern active flow control technology. Dielectric barrier discharge plasma can be used to induce localized velocity perturbations in air, so as to accomplish modifications to the global flow field. This paper presents a selective review of applications from the published literature with emphasis on interactions between plasma-induced perturbations and original unsteady fields of bluff-body flows. First, dielectric barrier discharge (DBD)-plasma actuator characteristics, and the local disturbance fields these actuators induce into the exterior flow, are described. Then, instabilities found in separated flows around bluff bodies that controlled actuation should target at are briefly presented. Key parameters for effective control are introduced using the nominally two-dimensional flow around a circular cylinder as a paradigm. The effects of the actuator configuration and location, amplitude and frequency of excitation, input waveform, as well as the phase difference between individual actuators are illustrated through examples classified based on symmetry properties. In general, symmetric excitation at frequencies higher than approximately five times the uncontrolled frequency of vortex shedding acts destructively on regular vortex shedding and can be safely employed for reducing the mean drag and lift fluctuations. Antisymmetric and symmetric excitation at low frequencies of the order of the natural frequency can amplify the wake instability and increase the mean and fluctuating aerodynamic forces, respectively, due to vortex locking-on to the excitation frequency or its subharmonics. Results from several studies show that the geometry and arrangement of the electrodes is of utmost significance. Power consumption is typically very low, but the electromechanical efficiency can be optimized by input waveform modulation.