2019
DOI: 10.1109/access.2019.2909071
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Hi-LASSO: High-Dimensional LASSO

Abstract: High-throughput genomic technologies are leading to a paradigm shift in research of computational biology. Computational analysis with high-dimensional data and its interpretation are essential for the understanding of complex biological systems. Most biological data (e.g., gene expression and DNA sequence data) are high-dimensional, but consist of much fewer samples than predictors. Such high-dimension, low sample size (HDLSS) data often cause computational challenges in biological data analysis. A number of … Show more

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Cited by 27 publications
(15 citation statements)
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“…LASSO regression performs L1 regularization and the aim is to get the subset of predictors that decrease the error rate of prediction for a target attribute [22].…”
Section: Machine Learning Algorithmsmentioning
confidence: 99%
“…LASSO regression performs L1 regularization and the aim is to get the subset of predictors that decrease the error rate of prediction for a target attribute [22].…”
Section: Machine Learning Algorithmsmentioning
confidence: 99%
“…where n denotes the exponent (n=2); min The Lasso is based on the following linear model [41]: where 0   is the shrinkage tuning parameter.…”
Section: B Contingency Filteringmentioning
confidence: 99%
“…We recently proposed a high-dimensional LASSO (Hi-LASSO) that theoretically improves the predictive power and feature selection performance on High-Dimension, Low Sample Size (HDLSS) data [8]. Hi-LASSO (1) alleviates bias introduced from bootstrapping, (2) satisfies the global oracle property, and (3) provides a Parametric Statistical Test for Feature Selection in Bootstrap regression modeling (PSTFSboot).…”
Section: Introductionmentioning
confidence: 99%