Hiccups: You got to be kidney me!

Nguyen, Viva; Deeb, Khaled; Rathakrishnan, Ranga

doi:10.1177/2050313x20962641

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…Intestinal and renal diseases may irritate the abdominal branches of the vagus nerve [ 2 ]. Hiccups have been reported in patients with renal abscess [ 5 ], giant hydronephrosis [ 6 ], acute tubular injury [ 7 ], and renal cell carcinoma [ 8 ]. Diseases irritating the diaphragm, such as liver abscesses, can cause hiccups [ 9 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

Prolonged hiccups induced by renal infarction: a case report

Kato,

Sato,

Hirose

et al. 2024

J Med Case Reports

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Background Hiccups are common symptoms that last for less than 48 hours. However, we encountered a case of renal infarction in a patient with prolonged hiccup. The relationship between hiccups and renal infarction is important in differentiating patients with prolonged hiccups. Case presentation An 87-year-old Japanese man with atrial fibrillation and receiving antithrombotic therapy presented to the emergency department with prolonged hiccups. The patient discontinued antithrombotic therapy for atrial fibrillation due to subcortical bleeding, after which he experienced right back pain. He was diagnosed with right renal infarction based on computed tomography images, and the antithrombotic therapy was continued. The patient’s hiccups ceased, and he was discharged on hospital day 11. Conclusion Hiccups can be induced by various clinical conditions. It is hypothesized that the inflammation of the right kidney infarction stimulated the diaphragm and induced prolonged hiccups in this patient; this theory is supported by the computed tomography images. This case report shows that internal organ diseases irritating the diaphragm can cause hiccups, and renal disease should be considered in patients with prolonged hiccups.

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Section: Discussionmentioning

confidence: 99%

Prolonged hiccups induced by renal infarction: a case report

Kato,

Sato,

Hirose

et al. 2024

J Med Case Reports

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Calcium/ibuprofen/noni fruit

2020

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Intractable Hiccups in a Patient With End-Stage Renal Disease: A Five-Month Ordeal Resolved Through Hemodialysis

Minoretti

2024

Cureus

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Hiccups, a common and usually self-limiting condition, are caused by involuntary, spasmodic contractions of the diaphragm and intercostal muscles, followed by the sudden closure of the glottis. While most cases resolve spontaneously, persistent hiccups (lasting 48 hours to one month) and intractable hiccups (lasting more than one month) require medical attention. Intractable hiccups, although rare, can significantly impair a patient's quality of life. The etiology of intractable hiccups is diverse, but they are often associated with serious underlying medical conditions, such as severe renal dysfunction and uremia. We present the case of a 72-year-old male patient with stage IV chronic kidney disease (CKD) who developed intractable, violent hiccups following a mild COVID-19 infection. Despite treatment attempts with chlorpromazine and baclofen, the hiccups persisted for five months and only resolved after the initiation of hemodialysis. Interestingly, the patient's renal function deteriorated significantly during the period of hiccup persistence, suggesting a possible link between the hiccups and the progression of CKD, likely exacerbated by COVID-19. This case highlights the challenges of managing intractable hiccups in patients with advanced CKD and emphasizes the importance of addressing underlying metabolic derangements in such complex clinical scenarios. Moreover, it contributes to the growing evidence supporting the role of dialysis in resolving intractable hiccups associated with severe renal dysfunction.

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Hiccups: You got to be kidney me!

Cited by 3 publications

References 12 publications

Prolonged hiccups induced by renal infarction: a case report

Prolonged hiccups induced by renal infarction: a case report

Calcium/ibuprofen/noni fruit

Intractable Hiccups in a Patient With End-Stage Renal Disease: A Five-Month Ordeal Resolved Through Hemodialysis

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