Hierarchical Assembly of Star Polymer Polymersomes into Responsive Multicompartmental Microcapsules

Xu, Weinan; Steinschulte, Alexander A.; Plamper, Felix A.; Korolovych, Volodymyr F.; Tsukruk, Vladimir V.

doi:10.1021/acs.chemmater.5b04934

Cited by 50 publications

(56 citation statements)

References 68 publications

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“…With the unique supramolecular architectures, they possess a combination of many preferential properties in the same system, granting the potential to be used for diverse requirements with a single application . The linear branching chains in star‐shaped polymers, for example, can be chemically modulated to fabricate stimuli‐responsive materials.…”

Section: Introductionmentioning

confidence: 99%

Nano‐Star‐Shaped Polymers for Drug Delivery Applications

Yang

Deen

et al. 2017

Macromol. Rapid Commun.

125

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With the advancement of polymer engineering, complex star-shaped polymer architectures can be synthesized with ease, bringing about a host of unique properties and applications. The polymer arms can be functionalized with different chemical groups to fine-tune the response behavior or be endowed with targeting ligands or stimuli responsive moieties to control its physicochemical behavior and self-organization in solution. Rheological properties of these solutions can be modulated, which also facilitates the control of the diffusion of the drug from these star-based nanocarriers. However, these star-shaped polymers designed for drug delivery are still in a very early stage of development. Due to the sheer diversity of macromolecules that can take on the star architectures and the various combinations of functional groups that can be cross-linked together, there remain many structure-property relationships which have yet to be fully established. This review aims to provide an introductory perspective on the basic synthetic methods of star-shaped polymers, the properties which can be controlled by the unique architecture, and also recent advances in drug delivery applications related to these star candidates.

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Section: Introductionmentioning

confidence: 99%

Nano‐Star‐Shaped Polymers for Drug Delivery Applications

Yang

Deen

et al. 2017

Macromol. Rapid Commun.

125

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“…As an example, in the group of Tsukruk recently were reported [60] dualloaded microcapsules based on assembly of star polymers. As an example, in the group of Tsukruk recently were reported [60] dualloaded microcapsules based on assembly of star polymers.…”

Section: Drug Deliverymentioning

confidence: 99%

How Can One Controllably Use of Natural ΔpH in Polyelectrolyte Multilayers?

Skorb

Möhwald

Andreeva

2016

Adv Materials Inter

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Most natural and synthetic polyelectrolytes (PEs) possess dissociable groups, and therefore the corresponding structures depend on pH. This enables manipulation of their properties, in special permeability, elasticity and swelling, and this can be made use of in many applications. The effect of individual polymer composition on the dissociation equilibrium is discussed. Different concentrations and pH values during the PE assembly affect concentration of charged groups per molecule on the dissociation equilibrium. Ionic strength also influences the protonation/deprotonation behavior of PE, that can be changed by adding different salt concentration but also varies with the concentration of charged groups in the polymer molecules. Electrostatic interactions of the polymer molecules strongly affect the dissociation equilibrium of weak PEs and, thus, layers architecture and properties that can be regulated by natural pH changes in such processes as self-healing, corrosion and antifouling, drug storage and delivery, etc

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“…[51] Recent developments in the area of multicompartment microcapsules include functionalization with polymersomes. [52] 3. Encapsulation into and release from microcapsules…”

Section: Multicompartmentalizationmentioning

confidence: 99%