Hierarchical lichee-like Fe₃O₄ assemblies and their high heating efficiency in magnetic hyperthermia*

Abstract

A nontoxic and biocompatible thermoseed is developed for the magnetic hyperthermia. Two kinds of thermoseed materials: hierarchical hollow and solid lichee-like Fe 3 O 4 assemblies, are synthesized by a facile hydrothermal method. The crystal structure of Fe 3 O 4 assemblies are characterized by x-ray diffraction, scanning electron microscopy, and transmission electron microscopy. Moreover, the prepared Fe 3 O 4 assemblies are used as a magnetic heat treatment agent, and their heating efficiency is investigated. Compared to solid assembly, hollow lichee-like Fe 3 O 4 assembly exhibits a higher specific absorption rate of 116.53 W/g and a shorter heating time, which is ascribed to its higher saturation magnetization, larger initial particle size, and the unique hierarchical hollow structure. Furthermore, the magnetothermal effect is primarily attributed to Néel relaxation. Overall, we propose a facile and convenient approach to enhance the heating efficiency of magnetic nanoparticles by forming hollow hierarchical assemblies.

Effect of bio-tissue deformation behavior due to intratumoral injection on magnetic hyperthermia

“…The concentration C i is then determined by the volume fraction θ i and the MNP density ρ as C i = θ i •ρ MNP . The individual power dissipation for MNP due to applied magnetic field can be illustrated by Rosensweig theory [36,37]…”

Reconstruction and stability of Fe3O4 (001) surface: An investigation based on particle swarm optimization and machine learning

“…Magnetite (Fe 3 O 4 ) attracts increasing attention due to its promising application in nanomedicine, [1][2][3][4][5] spintronics, [6,7] and catalysis. [8,9] At room temperature, magnetite crystallizes in an inverse spinel structure with oxygen anions arranged in a slightly distorted face centered cubic lattice and iron atoms occupying tetrahedral and octahedral interstitial sites.…”

Extraction method of nanoparticles concentration distribution from magnetic particle image and its application in thermal damage of magnetic hyperthermia

“…The heat produced by MNPs can locally rise the temperature in biological tissue during thermal therapy, and if the temperature inside biological tissue is kept within a specific range (42 • C to 46 • C), malignant cells are damaged and healthy cells are not much affected. [4][5][6] However, it is quite difficult to regulate the treatment temperature in the biological tissue during therapy, since the temperature field is normally affected by many factors, and the most important one is considered to be the concentration distribution of MNPs inside malignant biological tissue after magnetic nanofluid injection, which does not have accurate models. [7,8] Although the modeling of MNP concentration distribution has attracted much attention from the researchers in the last years, it is still difficult to have an accurate prediction, given its complexity and the diversity of resulting distributions.…”