1996
DOI: 10.1016/s0045-7825(96)01106-1
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Hierarchical modeling of heterogeneous bodies

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Cited by 159 publications
(84 citation statements)
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“…Reliable finite element model simulations of laser therapies can be computed in a fraction of the time that the actual therapy takes place. These prediction capabilities combined with an understanding of HSP kinetics and damage mechanisms at the cellular and tissue levels due to thermal stress, together with recent advances for controlling discretization and modeling errors through adaptive control strategies combined with the modern methods of inverse analysis, calibration, uncertainty quantification, sensitivity analysis, and optimization [12][13][14][15][16][17][18][19][20][21] provide a powerful methodology for planning and optimizing the delivery of thermo-therapy for cancer treatments. Moreover, from a computational point of view, changing the thermal delivery modality merely amounts to changing the source term in the governing PDE.…”
Section: Discussionmentioning
confidence: 99%
“…Reliable finite element model simulations of laser therapies can be computed in a fraction of the time that the actual therapy takes place. These prediction capabilities combined with an understanding of HSP kinetics and damage mechanisms at the cellular and tissue levels due to thermal stress, together with recent advances for controlling discretization and modeling errors through adaptive control strategies combined with the modern methods of inverse analysis, calibration, uncertainty quantification, sensitivity analysis, and optimization [12][13][14][15][16][17][18][19][20][21] provide a powerful methodology for planning and optimizing the delivery of thermo-therapy for cancer treatments. Moreover, from a computational point of view, changing the thermal delivery modality merely amounts to changing the source term in the governing PDE.…”
Section: Discussionmentioning
confidence: 99%
“…These methods are typically based on decomposing the macroscale problem and selective usage of computational techniques discussed in Refs. [5] and [376][377][378], employing a database to directly map the effective behavior from macroscopic information addressed in Refs. [379][380][381][382][383], transformation field analysis [384][385][386][387][388][389][390], or proper orthogonal/generalized decomposition [391-397].…”
Section: Analysis At the Rve Levelmentioning
confidence: 99%
“…ror estimates (indicators of a distance between the macroscopic response and the unknown response of the underlying microscopic structure) [1,[31][32][33][34][35]. Oden and Zohdi [36] developed an adaptive concurrent multiscale method for linear elastic problem with a posteriori error estimator for homogenisation.…”
Section: Introductionmentioning
confidence: 99%
“…In a special case, the error bound for the domain decomposition problem reduces to bounds on effective material properties which was proved to be identical to the Reuss-Voigt inequalities. The work was an extension to their previous paper [31] in which the fine scale discretisation error was ignored. The natural error between the exact solution u and the coarsest scale solution u (0,h) is defined by [43,44]:…”
Section: Introductionmentioning
confidence: 99%