Voltage and frequency regulation is one of the greatest challenges for proper operation subsequent to the isolated microgrid. To validate the satisfactory electric power quality supply to customers, the proposed manuscript tries to enhance the quality of energy provided by DG (Distributed generation) units connected to the subsequent isolated grid. Microgrid and simulation-based control structure including voltage and current control feedback loops is proposed for microgrid inverters to recover voltage and frequency of the system subsequently for any fluctuations in load change. The proportional-integral (PI) controller connected to the voltage controller is an end goal to obtain smooth response in most of the consistent frameworks. The present controller creates the space vector pulse width modulation signals which are given to the three-leg inverter. The objective elements of the multiobjective optimization issue are voltage overshoot and undershoot, rise time, settling time, and integral time absolute error (ITAE). The hybrid Multiobjective Symbiotic Organism Search (MOSOS) calculation is associated for self-tuning of control parameters keeping in mind the end goal to deal with the voltage and frequency. The proposed PI controller, along with the hybrid Multiobjective Symbiotic Organism Search algorithm, provides the solution for the greatest challenge of voltage and frequency regulation in an isolated-microgrid operation.