Hierarchically Structured Porous Materials–Applications in Biochemistry: Bioceramics, Life Science, and Drug Delivery

Hierarchical porous materials are widespread in nature and find an increasing number of applications as catalytic supports, biological scaffolds and lightweight structures. Recent advances in additive manufacturing and 3D printing technologies have enabled the digital fabrication of porous materials in the form of lattices, cellular structures and foams across multiple length scales. However, current approaches do not allow for the fast manufacturing of bulk porous materials featuring pore sizes that span broadly from macroscopic dimensions down to the nanoscale. Here, ink formulations are designed and investigated to enable 3D printing of hierarchical materials displaying porosity at the nano-, micro- and macroscales. Pores are generated upon removal of nanodroplets and microscale templates present in the initial ink. Using particles to stabilize the droplet templates is key to obtain Pickering nanoemulsions that can be 3D printed through direct ink writing. The combination of such self-assembled templates with the spatial control offered by the printing process allows for the digital manufacturing of hierarchical materials exhibiting thus far inaccessible multiscale porosity and complex geometries.

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Hierarchically Structured Porous Materials–Applications in Biochemistry: Bioceramics, Life Science, and Drug Delivery

Cited by 2 publications

References 81 publications

The processes behind drug loading and release in porous drug delivery systems

The processes behind drug loading and release in porous drug delivery systems

3D printing of sacrificial templates into hierarchical porous materials

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