High-altitude global amnesia

Litch, James A.; Bishop, Rachel A.

doi:10.1580/1080-6032(2000)011[0025:haga]2.3.co;2

Cited by 27 publications

(11 citation statements)

References 8 publications

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“…Otherwise, the absence of a female predominance in the literature may be explained by a bias of inclusion due to a focus on a specific issue. In effect, some of the authors were interested in TGA occurring at high altitude or triggered by the Valsalva-provoking activity, and these precipitating factors were exclusively observed in men (Litch and Bishop, 2000;Monzani et al, 2000;Savitz and Caplan, 2002;Bucuk et al, 2004;Schiefer and Sparing, 2005).…”

Section: Patient Demographymentioning

confidence: 99%

What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases

Quinette

2006

Brain

400

356

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Since the first reports of transient global amnesia (TGA) were published in 1956, several neuropsychological and functional imaging studies have shed light on different aspects of this neurological syndrome. By establishing diagnostic criteria, Hodges and Warlow (1990b) have made it far easier to identify clinical TGA-related features. However, no comprehensive survey has been yet carried out in order to validate their criteria/findings or provide information about previously unknown features. In the present paper, (i) we review the literature published since Hodges and Warlow's study and seek to characterize the demographic and clinical features of TGA more accurately, (ii) we report 142 personal TGA cases, with supplementary information regarding both episodes and patients, such as precipitating events, associated symptoms and personality, and (iii) we suggest the existence of different groups of TGA patients, on the basis of a hierarchical cluster analysis. This revealed that in women, episodes are mainly associated with an emotional precipitating event, a history of anxiety and a pathological personality. In men, they occur more frequently after a physical precipitating event. In younger patients, a history of headaches may constitute an important risk factor. No link was found with vascular risk factors. The relevance of each of the above-mentioned variables is discussed in the light of our classification. An extensive description of cases from both the literature and our patient population allows us to refine the characterization of clinical TGA features.

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Section: Patient Demographymentioning

confidence: 99%

What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases

Quinette

2006

Brain

400

356

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“…34 High-altitude global amnesia has been described as a self-limited episode of amnesia related to rapid ascent to a high altitude. 35 It is speculated that hyperventilation at high altitude causes hypocapnic cerebral vasoconstriction that contributes to transient focal neurological impairment, including memory deficits. 35 This entity can be differentiated from highaltitude cerebral edema by the lack of symptoms of acute mountain sickness such as headache, nausea, dizziness and fatigue.…”

Section: Discussionmentioning

confidence: 99%

“…35 It is speculated that hyperventilation at high altitude causes hypocapnic cerebral vasoconstriction that contributes to transient focal neurological impairment, including memory deficits. 35 This entity can be differentiated from highaltitude cerebral edema by the lack of symptoms of acute mountain sickness such as headache, nausea, dizziness and fatigue. 36 There is an association of TGA with factors of increased risk of cerebral venous thrombosis, such as polycythemia.…”

Section: Discussionmentioning

confidence: 99%

Transient global amnesia following a transoceanic flight

Rashid¹,

Starer

2006

Psychiatry Clin Neurosci

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Transient global amnesia (TGA) is the abrupt onset of temporary anterograde amnesia without any focal neurological features. It is a benign condition and is completely reversible in most cases. However, the sudden occurrence of memory impairment can be especially alarming to an individual who has recently arrived in an unfamiliar setting. The cause of TGA remains unknown. Reported here is the unusual occurrence of TGA in a man following the completion of an international airplane flight. Possible etiologies of the episode are considered.

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“…There is little information concerning the occurrence, the diagnosis, and the management of conversion dis-order in mountains. Several transient neurological or psychiatric events have been described at high altitude 6,7 directly related or not to hypoxia. A paper by Ryn 8 describes several psychopathologies in mountaineering at high altitude, such as the neurasthenic syndrome (apathetic-depressive or euphoric impulsive comportment), the cyclothymic syndrome, and the acute organic brain syndrome.…”

Section: Discussionmentioning

confidence: 99%