High animal protein diet and gut microbiota in human health

Cai, Jie; Chen, Zhongxu; Wu, Wei; Lin, Qinlu; Liang, Ying

doi:10.1080/10408398.2021.1898336

Cited by 49 publications

(38 citation statements)

References 166 publications

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“…The food which we ingest is also utilized by gut microbiota, and our dietary patterns allow shaping the composition and dominance of certain microbial species residing in the gut. For instance, consumption of diet containing high saturated fatty acids and high protein content can cause gut dysbiosis which has been linked to pathogenies of various ailments including autoimmune diseases, central nervous system disorders, and various infections [ 47 ].…”

Section: Modulatory Factors Of Gut Microbiotamentioning

confidence: 99%

Biodiversity of Gut Microbiota: Impact of Various Host and Environmental Factors

Anwar

Iftikhar

Muzaffar

et al. 2021

BioMed Research International

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Human bodies encompass very important symbiotic and mutualistic relationships with tiny creatures known as microbiota. Trillions of these tiny creatures including protozoa, viruses, bacteria, and fungi are present in and on our bodies. They play important roles in various physiological mechanisms of our bodies. In return, our bodies provide them with the habitat and food necessary for their survival. In this review, we comprehend the gut microbial species present in various regions of the gut. We can get benefits from microbiota only if they are present in appropriate concentrations, as if their concentration is altered, it will lead to dysbiosis of microbiota which further contributes to various health ailments. The composition, diversity, and functionality of gut microbiota do not remain static throughout life as they keep on changing over time. In this review, we also reviewed the various biotic and abiotic factors influencing the quantity and quality of these microbiota. These factors serve a significant role in shaping the gut microbiota population.

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Section: Modulatory Factors Of Gut Microbiotamentioning

confidence: 99%

Biodiversity of Gut Microbiota: Impact of Various Host and Environmental Factors

Anwar

Iftikhar

Muzaffar

et al. 2021

BioMed Research International

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“…The GI microbiota of healthy individuals was primarily composed of four phyla of bacteria: Firmicutes, Bacteroidetes, Proteobacteria , and Actinobacteria ( Wright et al, 2015 ). Furthermore, most of the microbiota was composed of the phyla Firmicutes and Bacteroidetes , and the class Clostridia dominated the Firmicutes sequences ( Cai et al, 2021 ). Of note, the microbiome includes not only bacteria, but also viruses, phage, fungi, archaea and so on ( Gong et al, 2021 ).…”

Section: The Development Of the Gut Microbiotamentioning

confidence: 99%

Pathogenesis of Children’s Allergic Diseases: Refocusing the Role of the Gut Microbiota

Dong

Yang

et al. 2021

Front. Physiol.

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Allergic diseases comprise a genetically heterogeneous cluster of immunologically mediated diseases, including asthma, food allergy (FA), allergic rhinitis (AR) and eczema, that have become major worldwide health problems. Over the past few decades, the spread of allergic diseases has displayed an increasing trend, and it has been reported that 22% of 1.39 billion people in 30 countries have a type of allergic disease. Undoubtedly, allergic diseases, which can be chronic, with significant morbidity, mortality and dynamic progression, impose major economic burdens on society and families; thus, exploring the cause of allergic diseases and reducing their prevalence is a top priority. Recently, it has been reported that the gastrointestinal (GI) microbiota can provide vital signals for the development, function, and regulation of the immune system, and the above-mentioned contributions make the GI microbiota a key player in allergic diseases. Notably, the GI microbiota is highly influenced by the mode of delivery, infant diet, environment, antibiotic use and so on. Specifically, changes in the environment can result in the dysbiosis of the GI microbiota. The proper function of the GI microbiota depends on a stable cellular composition which in the case of the human microbiota consists mainly of bacteria. Large shifts in the ratio between these phyla or the expansion of new bacterial groups lead to a disease-promoting imbalance, which is often referred to as dysbiosis. And the dysbiosis can lead to alterations of the composition of the microbiota and subsequent changes in metabolism. Further, the GI microbiota can affect the physiological characteristics of the human host and modulate the immune response of the host. The objectives of this review are to evaluate the development of the GI microbiota, the main drivers of the colonization of the GI tract, and the potential role of the GI microbiota in allergic diseases and provide a theoretical basis as well as molecular strategies for clinical practice.

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“…The versatile composition of human microbiota could enrich and stabilize the micro-environment. Personal habits or different biomedical processes such as metabolism [6], immune status [7], energy intake, and cell status [8] may heavily influence microbial composition. As a significant source of the genome, microbial communities could be used as a metric to assess the overall physical conditions of patients.…”

Section: Introductionmentioning

confidence: 99%

Oropharynx microbiota transitions in hypopharyngeal carcinoma treatment of induced chemotherapy followed by surgery

et al. 2021

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Aims To analyze changes in oropharynx microbiota composition after receiving induced chemotherapy followed by surgery for hypopharyngeal squamous cell carcinoma (HPSCC) patients. Methods Clinical data and swab samples of 38 HPSCC patients (HPSCC group) and 30 patients with benign disease (control group, CG) were enrolled in the study. HPSCC group was stratified into two groups: induced chemotherapy group (IC) of 10 patients and non-induced chemotherapy group (nIC) of 28 patients. The microbiota from oropharyngeal membrane was analyzed through 16S rRNA sequencing. Results Alpha-diversity (Shannon and Ace indexes) and weighted UniFrac based beta-diversity severely decreased in the HPSCC group when compared with CG. In pre-operative comparisons, PCoA and NMDS analyses showed microbial structures in the IC group were more similar to CG than nIC. Both IC group and nIC group yielded significantly diverse post-operative communities in contrast to their pre-operative counterparts, evident by the decrease in genera Veillonella and Fusobacterium and increase in genera Streptococcus and Gemella. Given that post-operative oropharynx microbiota showed no difference between IC and nIC groups, the IC group showed less accumulation in anaerobic communities. The abundance of genera Fusobacterium, Parvimonas, Actinomyces were enhanced in the advanced stages (III/IV). Conclusions Oropharynx microbiota in the HPSCC group presents dysbiosis with low diversity and abundance. Induced chemotherapy is beneficial in adjusting the oropharynx microbial environment leading to fewer amounts of anaerobe accumulation after operation. Higher amounts of Fusobacterium in advanced stages (III/IV) may influence the progression of HPSCC.

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High animal protein diet and gut microbiota in human health

Cited by 49 publications

References 166 publications

Biodiversity of Gut Microbiota: Impact of Various Host and Environmental Factors

Biodiversity of Gut Microbiota: Impact of Various Host and Environmental Factors

Pathogenesis of Children’s Allergic Diseases: Refocusing the Role of the Gut Microbiota

Oropharynx microbiota transitions in hypopharyngeal carcinoma treatment of induced chemotherapy followed by surgery

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